Table 5.6.a. Urinary enterolactone: Total population

Geometric mean and selected percentiles of urine concentrations (in µg/L) for the total U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

249

(227-273)

23.6

(19.6-29.5)

330

(303-370)

1710

(1500-1960)

5342

6–11 years

297

(251-352)

55.1

(41.1-73.7)

340

(288-412)

1420

(1250-2050)

727

12–19 years

256

(223-294)

31.5

(22.1-48.0)

317

(266-377)

1560

(1250-1900)

1490

20–39 years

237

(203-276)

20.3

(13.0-28.0)

317

(255-380)

1850

(1420-2320)

1139

40–59 years

231

(190-280)

15.9

(11.0-25.3)

334

(272-399)

1810

(1510-2240)

951

60 years and older

276

(245-311)

32.9

(17.9-50.3)

362

(303-417)

1680

(1330-2170)

1035

Males

Total, 6 years and older

258

(234-285)

21.7

(17.5-25.3)

349

(310-389)

1890

(1600-2280)

2594

6–11 years

322

(267-387)

55.3

(35.8-102)

363

(309-456)

1380

(1120-1810)

368

12–19 years

246

(212-287)

29.6

(19.4-41.7)

318

(252-391)

1560

(1250-1820)

733

20–39 years

249

(208-299)

19.2

(11.2-30.9)

337

(258-389)

2050

(1650-2540)

500

40–59 years

246

(194-312)

16.6

(12.7-25.3)

360

(278-438)

1940

(1580-2530)

480

60 years and older

274

(228-330)

19.9

(12.9-43.2)

361

(291-458)

1790

(1410-2470)

513

Females

Total, 6 years and older

241

(215-270)

25.9

(18.1-38.7)

321

(281-359)

1500

(1300-1810)

2748

6–11 years

273

(203-368)

55.5

(24.0-83.6)

325

(236-420)

1520

(847-2280)

359

12–19 years

267

(218-326)

37.2

(20.1-59.1)

314

(259-383)

1500

(1040-2130)

757

20–39 years

225

(181-279)

21.4

(9.30-38.4)

312

(239-381)

1450

(991-2000)

639

40–59 years

217

(164-288)

15.8

(7.30-44.9)

311

(227-399)

1510

(1180-1810)

471

60 years and older

277

(231-333)

43.4

(18.9-66.5)

362

(282-419)

1490

(1190-2140)

522

Table 5.6.b. Urinary enterolactone: Mexican Americans

Geometric mean and selected percentiles of urine concentrations (in µg/L) for Mexican Americans in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

236

(198-280)

32.0

(17.7-40.2)

316

(266-354)

1550

(1230-1890)

1492

6–11 years

209

(155-282)

31.4

(17.7-50.6)

265

(192-375)

913

(796-1420)

226

12–19 years

272

(238-312)

36.6

(29.5-61.7)

314

(253-370)

1650

(1350-1990)

538

20–39 years

262

(203-340)

34.5

(8.76-49.8)

346

(280-424)

1840

(1280-2620)

300

40–59 years

192

(149-249)

12.9

(8.00-35.8)

245

(200-347)

1390

(929-2060)

221

60 years and older

197

(137-285)

23.0

(6.66-50.5)

296

(180-415)

967

(825-1490)

207

Males

Total, 6 years and older

253

(200-320)

32.7

(15.7-46.3)

346

(266-416)

1640

(1000-2380)

722

6–11 years

236

(170-328)

35.1

(24.7-55.1)

316

(171-476)

972

(815-1800)

117

12–19 years

236

(210-266)

34.3

(21.7-55.3)

293

(210-357)

1510

(950-1900)

274

20–39 years

317

(225-446)

39.6

(6.81-79.5)

455

(280-628)

2380

(1280-3560)

127

40–59 years

166

(104-265)

10.4†

(4.10-38.8)

238

(148-389)

1030†

(647-2120)

105

60 years and older

266

(176-402)

37.2†

(6.66-99.7)

374

(248-488)

967†

(679-2570)

99

Females

Total, 6 years and older

218

(167-285)

30.2

(11.9-53.2)

279

(228-344)

1380

(980-1840)

770

6–11 years

184

(106-319)

16.8†

(<LOD-80.4)

236

(170-375)

847†

(745-1550)

109

12–19 years

319

(241-422)

56.1

(19.5-105)

352

(258-473)

1710

(1290-2530)

264

20–39 years

209

(134-328)

17.3

(2.91-77.7)

308

(183-414)

1100

(790-2580)

173

40–59 years

224

(159-316)

19.1

(3.44-58.0)

245

(193-392)

1480

(980-2200)

116

60 years and older

154

(96.7-246)

11.3†

(<LOD-43.0)

231

(148-322)

920†

(524-1490)

108

< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.6.c. Urinary enterolactone: Non-Hispanic blacks

Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic blacks in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

272

(230-322)

26.3

(17.6-43.6)

392

(339-441)

1500

(1270-1890)

1286

6–11 years

369

(297-457)

75.1

(41.0-99.1)

470

(391-521)

1520

(1220-2160)

249

12–19 years

351

(315-391)

53.9

(34.8-87.3)

428

(385-479)

1850

(1450-2340)

448

20–39 years

239

(167-344)

12.0

(5.40-49.4)

342

(248-504)

1680

(993-2300)

197

40–59 years

254

(202-320)

23.1

(14.5-45.9)

366

(283-479)

1350

(1050-1920)

210

60 years and older

237

(179-312)

15.2

(7.90-44.9)

399

(296-502)

1270

(1020-1960)

182

Males

Total, 6 years and older

266

(215-329)

20.9

(12.0-36.5)

416

(339-497)

1630

(1250-2080)

627

6–11 years

362

(304-430)

65.4

(21.5-107)

487

(341-524)

1370

(1070-1720)

127

12–19 years

330

(266-409)

38.6

(26.3-77.1)

422

(363-484)

1770

(1360-2440)

211

20–39 years

261

(163-417)

17.7†

(4.49-116)

416

(260-596)

1670†

(1000-2500)

91

40–59 years

235

(160-345)

16.6†

(4.20-34.6)

401

(184-559)

1350†

(741-2580)

109

60 years and older

183

(119-281)

6.00†

(3.30-19.5)

267

(155-488)

1290†

(1000-1980)

89

Females

Total, 6 years and older

278

(235-327)

39.1

(18.9-53.2)

360

(314-427)

1500

(1190-1870)

659

6–11 years

376

(259-547)

75.8

(28.7-130)

416

(299-664)

1740

(1050-2410)

122

12–19 years

374

(325-431)

87.3

(39.1-136)

441

(378-521)

1870

(1320-2260)

237

20–39 years

224

(152-330)

9.10†

(3.10-49.7)

314

(219-499)

1500†

(854-2140)

106

40–59 years

272

(218-340)

43.4†

(15.2-71.6)

358

(246-469)

1270†

(842-1540)

101

60 years and older

281

(197-401)

32.6†

(9.50-102)

438

(307-565)

1270†

(900-2210)

93

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.6.d. Urinary enterolactone: Non-Hispanic whites

Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic whites in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

259

(230-291)

23.9

(18.1-33.1)

344

(301-387)

1810

(1580-2100)

2112

6–11 years

308

(244-388)

57.5

(35.8-103)

331

(262-412)

1600

(1290-2310)

196

12–19 years

249

(203-306)

29.6

(17.5-58.1)

310

(242-384)

1620

(1200-2420)

375

20–39 years

235

(196-281)

19.1

(11.1-33.1)

317

(240-383)

1780

(1300-2180)

529

40–59 years

249

(195-319)

16.4

(9.30-34.1)

387

(278-424)

2030

(1610-2750)

434

60 years and older

297

(256-345)

44.8

(19.9-73.6)

372

(303-424)

1730

(1340-2260)

578

Males

Total, 6 years and older

272

(240-308)

22.9

(17.2-33.1)

360

(310-400)

1970

(1620-2450)

1038

6–11 years

336

(257-441)

70.2†

(35.8-152)

348

(283-474)

1390†

(881-2600)

101

12–19 years

242

(192-306)

23.2

(10.6-64.4)

316

(222-445)

1560

(1150-2180)

190

20–39 years

236

(185-300)

19.2

(11.0-32.3)

258

(209-389)

2000

(1300-2620)

231

40–59 years

290

(218-386)

17.3

(12.7-39.6)

424

(307-555)

2400

(1710-3540)

225

60 years and older

296

(236-372)

29.6

(12.9-62.1)

377

(292-492)

1750

(1310-2730)

291

Females

Total, 6 years and older

246

(212-286)

25.4

(15.8-43.7)

328

(280-383)

1490

(1290-2010)

1074

6–11 years

279

(185-420)

47.3†

(15.7-117)

325

(224-427)

1530†

(719-2900)

95

12–19 years

257

(189-349)

45.4

(17.5-62.1)

286

(222-403)

1800

(944-2950)

185

20–39 years

234

(176-310)

17.4

(7.50-43.7)

323

(238-431)

1310

(980-1970)

298

40–59 years

214

(148-310)

13.0

(5.28-46.1)

347

(206-418)

1660

(1010-2750)

209

60 years and older

298

(245-363)

53.0

(19.4-78.0)

348

(265-418)

1700

(1190-2240)

287

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.6.e. Urinary enterolactone: Total population (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for the total U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

233

(213-254)

21.2

(17.4-24.5)

309

(286-335)

1500

(1380-1630)

5342

6–11 years

323

(277-375)

69.3

(41.1-91.9)

375

(305-423)

1490

(1190-1780)

727

12–19 years

185

(163-211)

23.4

(15.2-31.9)

231

(206-256)

1110

(908-1330)

1490

20–39 years

190

(163-221)

14.0

(10.4-20.9)

278

(240-304)

1290

(1110-1520)

1139

40–59 years

232

(194-277)

16.3

(11.7-24.2)

315

(267-377)

1630

(1380-1940)

951

60 years and older

331

(286-383)

37.6

(20.3-65.1)

437

(380-492)

1860

(1540-2040)

1035

Males

Total, 6 years and older

208

(190-227)

17.4

(13.9-21.6)

279

(254-303)

1360

(1210-1540)

2594

6–11 years

339

(283-408)

76.0

(49.3-101)

397

(291-480)

1580

(1130-2120)

368

12–19 years

175

(152-201)

19.0

(12.9-29.6)

226

(200-247)

1090

(907-1310)

733

20–39 years

174

(143-210)

15.1

(10.4-22.6)

240

(206-276)

1180

(872-1530)

500

40–59 years

204

(165-253)

12.3

(8.16-24.2)

282

(243-350)

1420

(1150-1850)

480

60 years and older

257

(208-318)

18.2

(11.4-35.3)

380

(282-486)

1590

(1210-1940)

513

Females

Total, 6 years and older

259

(232-290)

27.9

(18.6-32.9)

342

(307-379)

1590

(1440-1800)

2748

6–11 years

306

(237-394)

55.4

(30.2-126)

343

(263-401)

1400

(1110-1610)

359

12–19 years

197

(163-237)

25.9

(16.2-36.8)

243

(198-306)

1150

(850-1490)

757

20–39 years

207

(165-259)

13.9

(8.20-27.9)

302

(259-360)

1370

(1120-1800)

639

40–59 years

261

(204-335)

18.7

(9.02-39.1)

355

(267-447)

1850

(1450-2300)

471

60 years and older

401

(339-474)

60.5

(30.9-103)

472

(404-562)

2020

(1590-2250)

522

Table 5.6.f. Urinary enterolactone: Mexican Americans (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for Mexican Americans in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

219

(191-252)

24.2

(18.6-33.2)

283

(258-328)

1270

(1030-1490)

1492

6–11 years

268

(200-359)

41.3

(20.8-64.7)

348

(240-437)

1190

(871-1980)

226

12–19 years

215

(185-250)

33.0

(18.7-49.5)

257

(215-296)

1110

(955-1310)

538

20–39 years

217

(174-270)

24.2

(9.46-37.2)

281

(242-398)

1410

(995-1730)

300

40–59 years

193

(146-254)

18.1

(6.78-23.3)

277

(214-371)

1220

(1020-1430)

221

60 years and older

227

(160-323)

25.3

(10.0-60.4)

334

(231-450)

1200

(985-1800)

207

Males

Total, 6 years and older

208

(169-257)

22.6

(14.9-36.1)

264

(227-328)

1270

(946-1730)

722

6–11 years

284

(191-421)

41.3

(12.9-83.0)

355

(217-504)

1840

(898-2790)

117

12–19 years

178

(152-208)

19.9

(14.6-43.8)

233

(184-281)

939

(716-1150)

274

20–39 years

233

(171-318)

26.9

(9.46-54.1)

280

(206-444)

1570

(868-2190)

127

40–59 years

140

(90.5-216)

8.37†

(3.50-22.6)

213

(126-282)

1030†

(597-1430)

105

60 years and older

251

(161-390)

26.8†

(3.62-67.2)

298

(206-503)

1390†

(989-2520)

99

Females

Total, 6 years and older

231

(193-277)

24.2

(11.1-58.9)

308

(273-366)

1280

(1070-1440)

770

6–11 years

252

(166-382)

28.5†

(<LOD-97.1)

319

(223-455)

1010†

(786-1490)

109

12–19 years

266

(208-339)

50.2

(18.0-87.9)

282

(225-373)

1400

(1030-1630)

264

20–39 years

199

(138-286)

13.3

(2.46-70.4)

280

(179-409)

1220

(981-1650)

173

40–59 years

270

(189-387)

21.9

(7.00-73.6)

394

(233-611)

1480

(1170-2140)

116

60 years and older

209

(135-324)

21.1†

(<LOD-63.0)

333

(154-422)

1070†

(773-1500)

108

< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.6.g. Urinary enterolactone: Non-Hispanic blacks (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic blacks in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

183

(153-220)

17.9

(12.0-29.9)

269

(219-309)

1090

(911-1230)

1286

6–11 years

345

(285-417)

76.0

(48.1-108)

429

(331-495)

1170

(972-1650)

249

12–19 years

197

(176-221)

32.3

(14.1-53.4)

244

(215-273)

931

(804-1180)

448

20–39 years

136

(92.9-199)

7.64

(3.17-26.6)

197

(138-288)

888

(628-1590)

197

40–59 years

172

(134-220)

15.8

(7.07-28.9)

251

(181-318)

1010

(678-1230)

210

60 years and older

222

(167-295)

15.7

(6.74-56.4)

341

(252-439)

1390

(872-1690)

182

Males

Total, 6 years and older

161

(128-202)

12.0

(7.64-31.9)

236

(197-278)

1010

(850-1220)

627

6–11 years

335

(272-413)

60.3

(38.6-112)

409

(329-507)

1100

(937-1570)

127

12–19 years

180

(147-221)

20.1

(11.8-45.1)

217

(186-271)

931

(728-1250)

211

20–39 years

126

(78.3-204)

7.64†

(1.31-32.6)

177

(125-242)

1100†

(556-1590)

91

40–59 years

143

(97.7-209)

9.30†

(2.81-28.1)

252

(152-319)

820†

(615-1420)

109

60 years and older

136

(86.0-215)

7.45†

(1.61-15.7)

220

(128-344)

885†

(705-1470)

89

Females

Total, 6 years and older

205

(172-245)

28.9

(17.0-37.7)

298

(241-340)

1090

(911-1390)

659

6–11 years

356

(270-468)

88.1

(59.4-126)

431

(279-552)

1180

(972-1670)

122

12–19 years

216

(187-250)

50.3

(24.3-69.9)

262

(221-298)

911

(686-1300)

237

20–39 years

144

(96.1-217)

12.1†

(2.05-37.2)

218

(142-326)

888†

(622-1670)

106

40–59 years

200

(157-256)

28.4†

(7.07-51.5)

247

(184-354)

1060†

(604-1440)

101

60 years and older

308

(214-443)

41.0†

(17.0-90.6)

428

(302-549)

1460†

(869-2020)

93

† Estimate is subject to greater uncertainty due to small cell size.

Table 5.6.h. Urinary enterolactone: Non-Hispanic whites (creatinine corrected)

Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic whites in the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.

Geometric mean
(95% conf. interval)

Selected percentiles (95% conf. interval)

Sample
size

10th

50th

90th

Males and Females

Total, 6 years and older

257

(229-289)

22.6

(17.1-27.9)

338

(308-377)

1630

(1460-1880)

2112

6–11 years

334

(277-402)

76.1

(48.9-108)

378

(291-435)

1580

(1220-2020)

196

12–19 years

189

(155-229)

22.8

(15.9-29.6)

238

(192-288)

1240

(900-1720)

375

20–39 years

205

(172-243)

14.5

(9.83-22.6)

296

(268-323)

1370

(1160-1640)

529

40–59 years

261

(210-326)

16.4

(10.2-29.9)

362

(282-444)

1850

(1410-2490)

434

60 years and older

371

(310-443)

44.3

(20.3-96.7)

468

(386-570)

1920

(1570-2200)

578

Males

Total, 6 years and older

230

(206-257)

21.2

(14.6-25.2)

308

(276-336)

1520

(1290-1690)

1038

6–11 years

370

(282-484)

82.0†

(69.3-123)

435

(247-601)

1780†

(1180-2940)

101

12–19 years

184

(146-233)

19.7

(7.43-31.9)

238

(189-287)

1210

(900-1880)

190

20–39 years

179

(141-227)

14.0

(9.83-24.7)

251

(201-309)

1270

(755-1630)

231

40–59 years

244

(189-316)

16.0

(8.16-29.9)

327

(254-433)

1630

(1240-2490)

225

60 years and older

283

(220-364)

19.6

(13.0-44.7)

424

(301-576)

1590

(1170-1980)

291

Females

Total, 6 years and older

287

(247-333)

27.9

(16.9-37.7)

370

(327-418)

1850

(1520-2020)

1074

6–11 years

299

(215-416)

55.2†

(25.1-142)

342

(249-401)

1400†

(847-1800)

95

12–19 years

194

(147-256)

21.7

(13.8-36.8)

241

(172-344)

1250

(783-1800)

185

20–39 years

233

(174-311)

14.0

(6.11-30.6)

322

(280-424)

1410

(1180-2010)

298

40–59 years

279

(204-383)

16.9

(6.44-48.4)

378

(281-532)

1930

(1450-2560)

209

60 years and older

457

(377-553)

76.3

(30.9-151)

513

(404-681)

2040

(1620-2580)

287

† Estimate is subject to greater uncertainty due to small cell size.