Table 5.4.a. Urinary O-desmethylangolensin: Total population
Geometric mean and selected percentiles of urine concentrations (in µg/L) for the total U.S. population aged6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
4.18
(3.65-4.78)
< LOD
4.00
(3.40-4.74)
98.7
(75.9-122)
5065
6–11 years
5.97
(4.69-7.59)
< LOD
6.50
(4.63-9.68)
105
(59.6-176)
683
12–19 years
5.87
(4.59-7.50)
< LOD
6.47
(4.47-8.60)
122
(99.0-152)
1411
20–39 years
3.59
(2.91-4.43)
< LOD
3.03
(2.50-4.10)
121
(70.1-189)
1085
40–59 years
4.67
(3.64-5.98)
< LOD
4.30
(3.20-5.50)
111
(66.1-160)
896
60 years and older
2.94
(2.39-3.62)
< LOD
3.01
(1.90-4.12)
63.9
(40.3-73.7)
990
Males
Total, 6 years and older
4.24
(3.58-5.01)
< LOD
4.22
(3.50-5.29)
102
(74.2-137)
2462
6–11 years
6.61
(4.59-9.51)
< LOD
8.40
(3.96-11.3)
121
(52.7-235)
345
12–19 years
6.19
(4.51-8.50)
< LOD
7.00
(4.22-10.6)
105
(74.1-148)
690
20–39 years
3.44
(2.53-4.66)
< LOD
3.00
(2.00-4.47)
135
(53.9-259)
474
40–59 years
4.49
(3.45-5.86)
< LOD
4.50
(2.80-6.30)
108
(57.3-160)
455
60 years and older
3.18
(2.56-3.95)
< LOD
3.60
(2.43-5.57)
58.4
(36.3-85.2)
498
Females
Total, 6 years and older
4.12
(3.55-4.79)
< LOD
3.90
(3.00-4.56)
93.3
(70.9-128)
2603
6–11 years
5.38
(4.06-7.12)
< LOD
5.10
(3.43-8.80)
88.5
(59.2-161)
338
12–19 years
5.56
(4.09-7.55)
< LOD
5.69
(3.63-7.80)
137
(85.6-195)
721
20–39 years
3.75
(2.85-4.95)
< LOD
3.11
(2.40-4.90)
94.8
(57.2-228)
611
40–59 years
4.84
(3.43-6.82)
< LOD
4.10
(2.83-5.51)
125
(64.9-233)
441
60 years and older
2.77
(2.05-3.73)
< LOD
2.40
(1.50-4.00)
68.0
(33.8-81.6)
492
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
Geometric mean and selected percentiles of urine concentrations (in µg/L) for Mexican Americans in the U.S.population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
2.43
(1.78-3.34)
< LOD
1.80
(1.00-2.84)
86.0
(59.7-105)
1400
6–11 years
3.17
(2.23-4.49)
< LOD
2.84
(1.70-4.04)
61.5
(36.8-129)
212
12–19 years
3.07
(2.35-4.01)
< LOD
2.49
(1.83-3.50)
98.0
(65.2-137)
508
20–39 years
*
< LOD
1.40
(<LOD-3.40)
87.8
(44.2-129)
282
40–59 years
*
< LOD
1.30
(.700-3.60)
95.2
(36.5-191)
209
60 years and older
*
< LOD
.420
(<LOD-2.40)
25.2
(16.0-37.9)
189
Males
Total, 6 years and older
2.70
(1.77-4.13)
< LOD
2.10
(.800-4.70)
90.9
(66.4-129)
686
6–11 years
3.72
(2.29-6.02)
< LOD†
3.75
(1.60-8.50)
60.2†
(29.3-140)
111
12–19 years
3.32
(2.53-4.36)
< LOD
3.20
(2.00-5.02)
86.5
(61.0-144)
262
20–39 years
*
< LOD
1.31
(<LOD-6.54)
97.6
(59.7-189)
122
40–59 years
2.49
(1.48-4.19)
< LOD†
1.30
(.500-4.70)
122†
(28.3-237)
100
60 years and older
*
< LOD†
.420
(<LOD-3.30)
17.0†
(8.73-34.6)
91
Females
Total, 6 years and older
2.16
(1.63-2.87)
< LOD
1.62
(.880-2.50)
70.9
(40.6-90.1)
714
6–11 years
2.67
(1.88-3.81)
< LOD†
2.28
(1.44-3.30)
55.0†
(20.3-129)
101
12–19 years
2.80
(1.86-4.23)
< LOD
2.40
(1.25-3.60)
98.0
(48.2-152)
246
20–39 years
*
< LOD
1.39
(<LOD-2.83)
57.4
(25.2-88.3)
160
40–59 years
*
< LOD†
1.00
(<LOD-5.20)
86.0†
(18.6-191)
109
60 years and older
*
< LOD†
< LOD
33.2†
(18.4-150)
98
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
* Not calculated. Proportion of results below limit of detection was too high to provide a valid result.
Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic blacks in the U.S.population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
5.54
(4.63-6.64)
< LOD
6.40
(5.10-7.98)
116
(95.5-155)
1219
6–11 years
10.6
(7.78-14.5)
< LOD
13.4
(9.40-22.5)
226
(157-303)
235
12–19 years
10.5
(7.71-14.3)
< LOD
13.2
(8.40-17.8)
165
(131-238)
424
20–39 years
4.69
(2.93-7.51)
< LOD
5.55
(2.66-9.30)
103
(52.4-161)
187
40–59 years
4.42
(2.98-6.55)
< LOD
4.67
(2.40-8.71)
87.6
(58.0-114)
199
60 years and older
3.33
(1.97-5.64)
< LOD
3.04
(1.20-5.70)
99.1
(33.4-357)
174
Males
Total, 6 years and older
6.36
(4.70-8.59)
< LOD
7.20
(4.80-10.2)
143
(105-177)
590
6–11 years
13.2
(8.14-21.3)
< LOD
22.5
(10.1-39.1)
250
(158-355)
121
12–19 years
12.2
(8.73-17.0)
< LOD
14.5
(7.90-20.7)
171
(136-394)
194
20–39 years
5.91
(3.47-10.1)
< LOD†
5.93
(2.60-14.3)
128†
(52.4-308)
85
40–59 years
3.78
(2.07-6.90)
< LOD†
3.50
(1.10-9.30)
99.4†
(31.4-120)
103
60 years and older
4.09
(2.10-7.93)
< LOD†
5.30
(1.18-7.60)
77.4†
(33.7-255)
87
Females
Total, 6 years and older
4.94
(4.05-6.02)
< LOD
5.69
(4.50-7.90)
100
(73.8-128)
629
6–11 years
8.38
(5.30-13.2)
< LOD
10.4
(5.53-13.6)
147
(64.2-281)
114
12–19 years
9.07
(5.81-14.2)
< LOD
11.8
(6.64-20.1)
141
(95.1-201)
230
20–39 years
3.92
(2.22-6.93)
< LOD†
4.98
(1.40-9.40)
79.7†
(26.6-191)
102
40–59 years
5.04
(2.88-8.81)
< LOD†
5.30
(2.10-13.3)
81.6†
(40.2-313)
96
60 years and older
2.89
(1.62-5.16)
< LOD†
2.70
(.700-5.31)
99.1†
(21.0-502)
87
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
Geometric mean and selected percentiles of urine concentrations (in µg/L) for non-Hispanic whites in the U.S.population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
4.25
(3.59-5.04)
< LOD
3.98
(3.30-4.80)
98.7
(72.8-135)
2021
6–11 years
5.98
(4.20-8.50)
< LOD
6.97
(3.43-11.5)
88.0
(45.0-191)
181
12–19 years
6.26
(4.47-8.77)
< LOD
6.50
(4.00-10.0)
122
(76.9-172)
360
20–39 years
3.47
(2.58-4.66)
< LOD
2.80
(2.03-4.40)
129
(61.0-228)
511
40–59 years
5.40
(4.03-7.23)
< LOD
4.56
(3.31-6.40)
137
(76.4-202)
405
60 years and older
2.88
(2.23-3.71)
< LOD
2.83
(1.71-4.20)
58.4
(30.2-78.0)
564
Males
Total, 6 years and older
4.22
(3.44-5.18)
< LOD
4.12
(3.31-5.40)
96.8
(65.7-137)
995
6–11 years
6.33
(3.52-11.4)
< LOD†
7.20
(3.30-15.7)
88.0†
(43.4-311)
90
12–19 years
6.27
(4.21-9.32)
< LOD
6.50
(3.60-13.5)
103
(61.6-148)
181
20–39 years
2.95
(1.95-4.48)
< LOD
2.51
(1.20-4.47)
96.0
(25.2-260)
223
40–59 years
5.35
(4.05-7.06)
< LOD
5.28
(3.31-8.00)
111
(58.4-178)
213
60 years and older
3.27
(2.60-4.12)
< LOD
3.60
(1.90-6.00)
58.4
(29.9-98.9)
288
Females
Total, 6 years and older
4.29
(3.50-5.25)
< LOD
3.98
(2.79-4.98)
106
(70.6-154)
1026
6–11 years
5.63
(3.55-8.95)
< LOD†
5.90
(2.70-14.3)
72.2†
(30.5-176)
91
12–19 years
6.26
(3.92-10.0)
< LOD
6.40
(3.50-11.7)
166
(58.3-367)
179
20–39 years
4.05
(2.76-5.94)
< LOD
3.80
(2.05-5.71)
135
(51.2-250)
288
40–59 years
5.46
(3.47-8.59)
< LOD
4.30
(2.36-6.40)
154
(64.9-322)
192
60 years and older
2.59
(1.81-3.72)
< LOD
2.10
(1.21-4.05)
59.9
(17.7-85.1)
276
< LOD means less than the limit of detection, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
Table 5.4.e. Urinary O-desmethylangolensin: Total population(creatinine corrected)
Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for the total U.S.population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
3.91
(3.38-4.52)
< LOD
3.74
(3.09-4.50)
87.6
(69.8-108)
5065
6–11 years
6.62
(5.15-8.52)
< LOD
6.64
(4.63-10.6)
93.7
(65.0-144)
683
12–19 years
4.28
(3.25-5.65)
< LOD
4.45
(3.22-6.51)
76.5
(61.6-102)
1411
20–39 years
2.89
(2.33-3.59)
< LOD
2.63
(1.96-3.66)
87.8
(50.8-126)
1085
40–59 years
4.67
(3.70-5.90)
< LOD
3.87
(2.73-5.68)
112
(71.8-155)
896
60 years and older
3.51
(2.81-4.37)
< LOD
3.19
(2.12-4.95)
64.7
(50.8-76.0)
990
Males
Total, 6 years and older
3.43
(2.85-4.12)
< LOD
3.51
(2.56-4.45)
75.2
(58.5-96.5)
2462
6–11 years
7.12
(4.73-10.7)
< LOD
6.80
(3.59-17.0)
97.8
(56.2-233)
345
12–19 years
4.45
(3.20-6.19)
< LOD
4.71
(3.41-8.02)
70.2
(48.8-115)
690
20–39 years
2.40
(1.73-3.33)
< LOD
2.05
(1.38-3.06)
88.9
(34.3-151)
474
40–59 years
3.76
(2.88-4.92)
< LOD
3.66
(2.46-5.76)
80.3
(53.1-118)
455
60 years and older
2.96
(2.35-3.73)
< LOD
2.92
(1.84-4.68)
51.7
(35.4-64.2)
498
Females
Total, 6 years and older
4.43
(3.76-5.21)
< LOD
3.92
(3.15-5.00)
98.3
(70.3-140)
2603
6–11 years
6.14
(4.67-8.09)
< LOD
6.61
(4.42-10.5)
88.0
(52.7-158)
338
12–19 years
4.12
(2.97-5.71)
< LOD
3.87
(2.50-5.90)
89.5
(61.4-111)
721
20–39 years
3.45
(2.58-4.61)
< LOD
3.62
(2.28-4.64)
86.0
(43.2-155)
611
40–59 years
5.76
(4.18-7.94)
< LOD
3.90
(2.69-7.27)
147
(85.2-280)
441
60 years and older
4.00
(2.93-5.47)
< LOD
3.40
(1.92-6.17)
69.8
(56.9-109)
492
< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.
Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for Mexican Americansin the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
2.26
(1.70-3.00)
< LOD
1.69
(1.12-2.67)
58.8
(48.6-87.8)
1400
6–11 years
4.11
(3.09-5.47)
< LOD
3.69
(2.16-7.00)
79.8
(53.6-114)
212
12–19 years
2.43
(1.85-3.19)
< LOD
2.13
(1.55-3.17)
61.5
(47.4-86.3)
508
20–39 years
*
< LOD
1.17
(<LOD-2.67)
56.4
(29.9-103)
282
40–59 years
*
< LOD
1.56
(.805-3.55)
58.8
(27.8-145)
209
60 years and older
*
< LOD
1.03
(<LOD-2.70)
30.4
(21.4-55.3)
189
Males
Total, 6 years and older
2.23
(1.52-3.27)
< LOD
1.64
(.932-3.90)
61.4
(48.6-93.0)
686
6–11 years
4.52
(2.88-7.09)
< LOD†
4.87
(1.72-8.95)
93.0†
(50.2-145)
111
12–19 years
2.50
(1.87-3.35)
< LOD
2.82
(1.54-4.31)
56.1
(37.2-71.2)
262
20–39 years
*
< LOD
1.45
(<LOD-4.56)
60.0
(25.8-113)
122
40–59 years
2.04
(1.26-3.32)
< LOD†
1.42
(.661-4.23)
57.2†
(19.6-218)
100
60 years and older
*
< LOD†
.698
(<LOD-3.02)
23.6†
(11.1-33.2)
91
Females
Total, 6 years and older
2.30
(1.77-2.99)
< LOD
1.69
(1.17-2.08)
57.7
(41.7-87.6)
714
6–11 years
3.73
(2.62-5.29)
< LOD†
2.44
(1.68-7.00)
78.3†
(27.1-108)
101
12–19 years
2.35
(1.57-3.52)
< LOD
1.78
(1.10-2.78)
68.3
(45.6-115)
246
20–39 years
*
< LOD
1.03
(<LOD-2.15)
41.7
(15.5-87.6)
160
40–59 years
*
< LOD†
1.77
(<LOD-3.90)
76.8†
(29.1-145)
109
60 years and older
*
< LOD†
< LOD
55.3†
(20.9-970)
98
< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
* Not calculated. Proportion of results below limit of detection was too high to provide a valid result.
Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic blacksin the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
3.73
(3.08-4.51)
< LOD
4.12
(3.20-5.48)
71.9
(54.7-100)
1219
6–11 years
9.94
(7.43-13.3)
< LOD
10.6
(8.27-18.2)
217
(118-305)
235
12–19 years
5.88
(4.34-7.98)
< LOD
7.25
(4.64-10.2)
95.0
(57.0-142)
424
20–39 years
2.68
(1.70-4.23)
< LOD
3.66
(1.67-5.69)
45.4
(26.8-100)
187
40–59 years
2.95
(2.07-4.19)
< LOD
2.93
(1.61-5.48)
60.4
(36.7-81.9)
199
60 years and older
3.11
(1.99-4.85)
< LOD
2.91
(1.64-4.83)
75.6
(47.2-167)
174
Males
Total, 6 years and older
3.84
(2.85-5.19)
< LOD
4.45
(2.64-7.30)
79.7
(55.2-118)
590
6–11 years
12.3
(7.52-20.0)
< LOD
18.0
(9.43-32.4)
233
(119-363)
121
12–19 years
6.63
(4.79-9.18)
< LOD
7.65
(4.69-11.1)
109
(59.1-198)
194
20–39 years
2.87
(1.70-4.84)
< LOD†
2.95
(1.28-8.61)
42.9†
(23.4-100)
85
40–59 years
2.27
(1.24-4.17)
< LOD†
2.18
(.996-5.61)
67.8†
(23.2-84.4)
103
60 years and older
3.05
(1.64-5.69)
< LOD†
2.79
(1.12-5.83)
79.7†
(26.3-151)
87
Females
Total, 6 years and older
3.63
(2.96-4.46)
< LOD
4.05
(3.26-5.22)
64.4
(47.0-90.4)
629
6–11 years
7.89
(5.57-11.2)
< LOD
8.27
(4.80-10.9)
104
(62.9-305)
114
12–19 years
5.24
(3.35-8.21)
< LOD
5.83
(3.15-11.1)
71.9
(47.5-142)
230
20–39 years
2.54
(1.45-4.46)
< LOD†
3.36
(1.42-5.69)
42.1†
(22.1-185)
102
40–59 years
3.67
(2.23-6.04)
< LOD†
3.61
(1.61-7.58)
54.4†
(34.1-147)
96
60 years and older
3.14
(1.90-5.19)
< LOD†
2.91
(1.31-6.30)
75.6†
(23.8-359)
87
< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.
Geometric mean and selected percentiles of urine concentrations (in µg/g creatinine) for non-Hispanic whitesin the U.S. population aged 6 years and older, National Health and Nutrition Examination Survey, 1999–2002.
Geometric mean (95% conf. interval)
Selected percentiles (95% conf. interval)
Sample size
10th
50th
90th
Males and Females
Total, 6 years and older
4.24
(3.55-5.07)
< LOD
3.78
(3.05-4.95)
97.4
(71.8-125)
2021
6–11 years
6.69
(4.67-9.58)
< LOD
6.80
(3.78-13.6)
85.2
(47.9-190)
181
12–19 years
4.79
(3.27-7.03)
< LOD
4.70
(3.14-8.91)
83.6
(60.3-125)
360
20–39 years
3.01
(2.28-3.98)
< LOD
2.72
(1.89-3.77)
97.4
(50.8-151)
511
40–59 years
5.67
(4.36-7.37)
< LOD
5.32
(2.96-7.96)
136
(71.8-210)
405
60 years and older
3.56
(2.74-4.64)
< LOD
3.17
(1.83-5.45)
64.5
(45.6-83.0)
564
Males
Total, 6 years and older
3.60
(2.89-4.49)
< LOD
3.51
(2.54-4.68)
76.4
(54.1-102)
995
6–11 years
7.20
(3.84-13.5)
< LOD†
6.80
(2.85-21.3)
90.2†
(39.0-407)
90
12–19 years
4.85
(3.15-7.46)
< LOD
4.71
(3.05-13.5)
62.2
(45.9-125)
181
20–39 years
2.24
(1.48-3.39)
< LOD
1.96
(1.27-3.06)
88.2
(23.5-151)
223
40–59 years
4.56
(3.50-5.94)
< LOD
4.91
(2.73-7.08)
96.5
(43.2-161)
213
60 years and older
3.12
(2.43-4.01)
< LOD
3.17
(1.83-5.10)
49.3
(31.6-76.0)
288
Females
Total, 6 years and older
4.97
(4.04-6.10)
< LOD
4.15
(3.15-6.03)
120
(72.2-153)
1026
6–11 years
6.19
(4.04-9.49)
< LOD†
6.86
(3.85-13.6)
84.7†
(37.9-179)
91
12–19 years
4.74
(2.93-7.67)
< LOD
4.64
(2.43-8.27)
98.9
(61.4-292)
179
20–39 years
4.01
(2.77-5.79)
< LOD
4.01
(2.52-5.73)
97.4
(45.6-165)
288
40–59 years
7.07
(4.69-10.7)
< LOD
5.35
(2.45-10.1)
159
(97.6-421)
192
60 years and older
3.96
(2.70-5.81)
< LOD
2.86
(1.64-6.60)
71.5
(49.1-114)
276
< LOD means less than the limit of detection for the uncorrected urine value, which may vary for some compounds by year. See Appendix D for LOD.
† Estimate is subject to greater uncertainty due to small cell size.