Interventions that include the following combination of interventions are recommended based on strong evidence of their effectiveness in increasing targeted vaccination coverage: an intervention to enhance access to vaccination services (expanded access in healthcare settings, reduced client out-of-pocket costs), and at least one provider- or system-based intervention (standing orders, provider reminder systems, provider assessment and feedback), and/or at least one intervention to increase client demand for vaccination (client reminders, client education). Combinations of specific interventions have proven effective at increasing targeted vaccine coverage.