This publication offers a comprehensive collection of 70 “building blocks,” which are primary prevention strategies that merit consideration by state and local governments and others in position to reduce exposure to hazards in housing and thereby help meet the Healthy People 2020 objective of reducing blood lead levels in children. Exemplary strategies span a broad spectrum that includes targeting high-risk properties; widely instituting safe work practices; building community capacity to check for hazards and work safety; delivering hazard assessment, control, and prevention services; motivating action; screening high-risk housing; expanding financial resources; strengthening enforcement; raising public awareness and support; and establishing valuable partnerships.