Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Open for Recruitment

The gene p53 suppresses cancer and inflammation in the body, and NIEHS investigators speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage. This study wants blood samples from participants to find out how the changes in p53 lead to these conditions.

Research has shown that certain proteins in cells may be linked to higher risk of developing inflammation, tumors, and other medical problems. By examining how the blood cells of healthy volunteers respond to environmental exposures, researchers hope to better understand the relationship of genes, environmental factors, and human diseases.

For more information on this study, please visit the Clinical Trials Study page.