State departments of health and agriculture in several states, collaborating local health jurisdictions, CDC, and the United States Department of Agriculture’s Food Safety and Inspection Service (USDA-FSIS) are investigating a multi-state outbreak of Escherichia coli O157:H7 infections. As of July 17, 2008, 49 confirmed cases have been linked both epidemiologically and by molecular fingerprinting to this outbreak. The number of cases in each state is as follows: Georgia (4), Indiana (1), Kentucky (1), Michigan (20), New York (1), Ohio (21), and Utah (1). Their illnesses began between May 27 and July 1, 2008. Twenty-seven persons have been hospitalized. One patient developed a type of kidney failure called hemolytic-uremic syndrome (HUS). No deaths have been reported. Twenty-eight (57%) patients are female. The ages of patients range from 4 to 78 years; 47% are between 10 and 24 years old (only 21% of the U.S. population is in this age group).