Toxicological Profiles
Information About Contaminants Found at Hazardous Waste Sites
Substance Index for ToxProfiles
Finalized toxicological profiles by chemical with NTIS order number. Updates are in bold.
*
denotes tox profiles funded by the Department of Defense.
D
1,1-Dichloroethane (Final)
1,1-Dichloroethene (Updated) (PB/95/100152/AS)
1,2-Dibromo-3-Chloropropane (PB/93/110906/AS)
1,2-Dibromoethane (PB/93/110740/AS)
1,2-Dichloroethane (Updated) (PB/2001/109103/AS)
1,2-Dichloroethene (Updated) (PB/97/121081/AS)
1,2-Dichloropropane (PB/90/182122/AS)
1,2-Diphenylhydrazine (Updated) (PB/91/180356/AS)
1,3 Dinitrobenzene & 1,3,5 Trinitrobenzene (PB/95/264289/AS)*
1,4-Dioxane (PB2013-105794)
2,4-Dichlorophenoxyacetic Acid (2,4-D) (Draft for Public Comment)
3,3'-Dichlorobenzidine (Updated) (PB/99/121980)
DDT, DDE, DDD (Updated) (PB2003-100137)
DEET (N,N-diethyl-meta-toluamide)
Di(2-ethylhexyl)phthalate (DEHP) (Updated) (PB2003-100138)
Di-n-butyl Phthalate (Updated) (PB/2001/109104/AS)
Di-n-octylphthalate (DNOP) (PB/98/101033/AS)*
Diazinon (Updated) (PB2009-100003)
Dichlorobenzenes (Updated) (PB2007-100672)
Dichloropropenes (Updated) (PB2009-100004)
Dichlorvos (PB/98/101124/AS)
Diethyl phthalate (PB/95/264214/AS)*
Diisopropyl Methylphosphonate (DIMP) (PB/99/102535/AS)*
Dinitrocresols (Updated) (PB/95/264321)
Dinitrophenols (PB/95/264339)
Dinitrotoluenes (Updated)
Disulfoton (PB/95/264347)
L
Lead (Updated) (PB2008-100007)
P
Parathion
Pentachlorophenol (Updated) (PB/2001/109106/AS)
Perchlorates (Updated) (PB2009-100006)
Perfluoroalkyls (Draft for Public Comments)
Phenol (Updated) (PB2009-100007)
Phosphate Ester Flame Retardants (PB2013-105796)
Plutonium (Updated) (PB2010-100006)
Polybrominated Biphenyls (PBBs) (Updated) (PB2004-107334)
Polybrominated Diphenyl Ethers (PBDEs) (Updated)
Polychlorinated Biphenyls (PCBs) (Updated) (PB/2000/108027)
Polycyclic Aromatic Hydrocarbons (PAHs) (Updated) (PB/95/264370) Acenaphthene, Acenaphthylene, Anthracene, Benzo(a)anthracene, Benzo(a)pyrene, Benzo(b)fluoranthene, Benzo(g,h,i)perylene, Benzo(k)fluoranthene, Chrysene, Dibenzo(a,h)anthracene, Fluoranthene, Fluorene, Indeno(1,2,3-cd)pyrene, Phenanthrene, Pyrene
Propylene Glycol (Updated) (PB2009-103929)*
Pyrethrins and Pyrethroids (PB2004-100004)
Pyridine (PB/93/110831/AS)
T
1,1,1-Trichloroethane (Updated) (PB/95/264396)
1,1,2,2-Tetrachloroethane (Updated) (PB2009-100008)
1,1,2-Trichloroethane (PB/90/196411/AS)
1,2,3 Trichloropropane (PB/93/110872/AS)
1,3,5 Trinitrobenzene & 1,3 Dinitrobenzene (PB/95/264289/AS)* (See 1,3-Dinitrobenzene)
2,4,6-Trinitrotoluene (TNT) (PB/95/264297/AS)*
Tetrachloroethylene (PERC) (Updated) (Draft for Public Comment)
Tetryl (PB/95/264271/AS)*
Thallium (PB/93/110856/AS)
Thorium (PB/91/180448/AS)
Tin and Compounds (Updated) (PB2006-100006)
Titanium Tetrachloride (PB/98/101082/AS)*
Toluene (Updated)
Toluene Diisocyanate / Methylenediphenyl Diisocyanate (Draft for Public Comment)
Total Petroleum Hydrocarbons (TPH) (PB/99/163370)
Toxaphene (Updated) (Final)
Trichlorobenzenes (Final)
Trichloroethylene (TCE) (Updated) (Draft for Public Comment)
Tungsten (PB2006-100007)
Z
Zinc (Updated) (PB2006-100008)
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Tox Profiles Under Consideration
ACRYLONITRILE
2-BUTANONE
CHLOROBENZENE
CHLORODIBENZOFURANS
DINITROPHENOLs
ENDRIN
MIREX & CHLORDECONE
THORIUM
1,1,2-TRICHLOROETHANE
VINYL ACETATE
Tox Profiles In Development
Bromodichloromethane
Bromomethane
1,1-Dichloroethene
1,2-Dichloropropane
DDT,DDD, DDE
Glyphosate
2-Hexanone
Lead
Perfluoroalkyls
Pyrethrins
S,S,S-Tributyl Phosphorotrithioate (Tribufos)
Bis(2-chloroethyl)ether
Bis(chloromethyl)ether
1,2-Diphenylhydrazine
N-Nitrosodiphenylamine
N-Nitrosodi-n-propylamine
Tetrachloroethylene
Toluene Diisocyanate
Trichloroethylene
Chlordane
1,2-Dibromo-3-chloropropane
1,2-Dichloroethene
Dintrocresols
Hexachlorobutadiene
Isophorone
MBOCA
1,2,3-Trichloropropane
Tox Profiles Released for Public Comment
Tox Profiles Recently Finalized
Background
By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.
Toxicological profiles are developed in two stages:
(1) DRAFTS : The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Human Health Sciences.
(2) FINALS : After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles.
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Profile Development: