2015-2018 Advanced Molecular Detection (AMD) Study (MN, TN) — CDC is partnering with the MN Department of Health, Mayo Clinic, TN Department of Health, and Vanderbilt University to obtain up to 30,000 clinical specimens from patients with suspected tickborne illness over a 3-year period. CDC will use AMD methods (16s metagenomics) to identify the specific tickborne bacteria that caused these patients’ illnesses. This multi-disciplinary project will build critical molecular and bioinformatics capacity that will help advance tickborne disease detection and surveillance.
2014-2016 Cost of Lyme Disease (COLD) study — A prospective, descriptive study among Lyme disease patients in CT, MD, MN, and NY to assess total societal and individual level costs of Lyme disease.
2012-16 Bait Box Intervention (CT) — A prospective, blinded, placebo-controlled trial to evaluate the efficacy of commercially available, rodent-targeted bait boxes to prevent Lyme and other tickborne diseases in humans.
Pilot study began in 2012 with 125 households.
In 2013, the study expanded to 500 additional households.
2011-12 Lyme and Other Tickborne Diseases Prevention Study (CT, MD, NY) — A prospective, blinded, placebo-controlled trial of 2700 households to evaluate the efficacy of a single springtime application of commercially available, EPA-registered acaricide (bifenthrin) to prevent Lyme and other tickborne diseases in humans.
Underreporting Study (MD, MN, NY) — Study to determine the degree to which Lyme and other tickborne diseases are underreported and explore methods to enhance surveillance.
Laboratory Survey (CT, MD, MN, NY) — A survey of major commercial testing labs to determine current testing methods and volume for common tickborne diseases. Researchers used survey data from large commercial laboratories in the United States to estimate the cost of testing and number of infections among patients from whom specimens were submitted.
