| 4154 |
National Institute of Environmental Health Sciences |
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en |
Innate Immunity Signal Transduction in Human Leukocytes |
The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream. |
| blood cell function | 0.857637 |
| Innate Immunity Signal | 0.892013 |
| Recurrent fever | 0.691945 |
| research study | 0.739352 |
| participant | 0.580026 |
| Alcohol consumption | 0.680188 |
| white blood cells | 0.929239 |
| Blood pressure | 0.801272 |
| ml | 0.568081 |
| healthy adult donors | 0.845682 |
| Exposure Study | 0.739471 |
| Diarrhea | 0.538237 |
| Human Leukocytes | 0.724044 |
| dentist | 0.537883 |
| HMG CoA reductase | 0.857876 |
| BPA | 0.546679 |
| Insulin dependent diabetes | 0.82172 |
| CaREFREE Study | 0.753508 |
| Creutzfeldt-Jacob Disease | 0.671451 |
| Transduction | 0.541425 |
| lbs | 0.538272 |
| Calorie Restriction | 0.725628 |
| Ages Eligible | 0.706322 |
| Cox-2 Gene | 0.732119 |
|
| samples states | 0.670052 |
| Pulse rate | 0.661917 |
| suspected pregnancy | 0.691713 |
| Clinical Trials Study | 0.877316 |
| blood plasma | 0.738636 |
| corticosteroids | 0.544082 |
| inflammation | 0.538031 |
| cups | 0.554088 |
| possible disease-related conditions | 0.863689 |
| Bisphenol | 0.560014 |
| blood donation | 0.879466 |
| participants | 0.555679 |
| doctor visit | 0.690752 |
| bloodstream | 0.551006 |
| test tube | 0.68694 |
| substances | 0.570815 |
| Reproductive Effects | 0.70382 |
| immune cells | 0.891453 |
| antidepressants | 0.536599 |
| various signals | 0.700116 |
| Genders Eligible | 0.714599 |
| certain circumstances | 0.690168 |
| response | 0.580673 |
| antihistamines | 0.545714 |
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| 4156 |
National Institute of Environmental Health Sciences |
Html |
en |
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study |
Bisphenol A (BPA) is a chemical that is used primarily to make plastics, resins, and thermal paper. |
| North Carolina | 0.404904 |
| resins | 0.235977 |
| medical history | 0.381623 |
| research study | 0.407097 |
| breastfeeding female | 0.395992 |
| low levels | 0.422271 |
| single oral dose | 0.577155 |
| Clinical Research Unit | 0.864438 |
| study period | 0.420853 |
| Regular blood samples | 0.562795 |
| volunteers | 0.234926 |
| water | 0.268032 |
| screening laboratory tests | 0.527317 |
| follow-up visit | 0.532141 |
| body absorbs | 0.401547 |
| BPA | 0.950847 |
| vanilla wafer cookie | 0.53318 |
| chemical | 0.238196 |
| Research Triangle Park | 0.877312 |
| BPA dose | 0.678802 |
| single dose | 0.599445 |
| 24-hour urine collections | 0.632026 |
| thermal paper | 0.423385 |
| CRU | 0.462451 |
|
| baby bottles | 0.417986 |
| effort | 0.258764 |
| Environmental Health Sciences | 0.535257 |
| additional blood | 0.384898 |
| NIEHS Clinical Research | 0.632204 |
| follow-up visits | 0.628047 |
| plastic products | 0.416823 |
| frequent blood tests | 0.533259 |
| place | 0.235059 |
| National Institute | 0.383375 |
| participants | 0.371129 |
| plastics | 0.238144 |
| reproductive age | 0.38114 |
| Trials Study page | 0.566642 |
| urine tests | 0.663008 |
| people | 0.237954 |
| food | 0.237865 |
| 13-hour visit | 0.506357 |
| Researchers | 0.237427 |
| study visits | 0.443822 |
| ages | 0.234675 |
| compensation | 0.25884 |
| BPA-containing products | 0.397451 |
| time | 0.321999 |
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| 4157 |
National Institute of Environmental Health Sciences |
Html |
en |
Blood Vessel Study |
The endothelium is the inner lining of blood vessels. The cells in this lining help regulate blood flow and immune system function. |
| North Carolina | 0.593975 |
| certain diseases | 0.51467 |
| medical history | 0.592865 |
| Sample collections | 0.495826 |
| arteries | 0.42047 |
| research study | 0.513955 |
| Participants | 0.488437 |
| certain genes | 0.626794 |
| electrocardiogram | 0.425687 |
| informed consent | 0.506292 |
| genetic risk | 0.505664 |
| blood flow | 0.602203 |
| contact Grace Isshiki | 0.583686 |
| endothelial function | 0.644334 |
| single study visit | 0.622939 |
| Clinical Research Unit | 0.904054 |
| Sciences Clinical Research | 0.585233 |
| blood vessels | 0.593264 |
| urine samples | 0.514808 |
| artery | 0.445869 |
| Protocol Number | 0.496279 |
| Research Triangle Park | 0.923425 |
| inner lining | 0.614816 |
| problems | 0.433444 |
| immune system function | 0.514997 |
|
| endothelial cells | 0.557885 |
| healthy adults | 0.503616 |
| short-acting dose | 0.494919 |
| blood samples | 0.503224 |
| CRU | 0.449371 |
| short-acting medication | 0.499172 |
| NIEHS Clinical Research | 0.776132 |
| protocol procedures | 0.497126 |
| Clinical Trials Study | 0.600871 |
| study procedures | 0.506002 |
| current participant | 0.501346 |
| nitroglycerin | 0.442508 |
| heart disease | 0.514134 |
| Environmental Polymorphisms Registry | 0.586863 |
| place | 0.433692 |
| arm | 0.436358 |
| National Institute | 0.496202 |
| endothelium | 0.431348 |
| ultrasound | 0.436314 |
| high blood pressure | 0.619133 |
| information | 0.466386 |
| compensation | 0.428407 |
| time | 0.433266 |
| physical exam | 0.59612 |
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| 4169 |
National Institute of Environmental Health Sciences |
Html |
en |
Cockroaches |
Cockroaches are one of the most common and allergenic of indoor pests. |
| pet food | 0.645045 |
| water sources | 0.641687 |
| allergenic proteins | 0.934776 |
| cleanest | 0.438118 |
| wash countertops | 0.676855 |
| leaky faucets | 0.714112 |
| tight-lidded containers | 0.663648 |
| Plug | 0.376362 |
| indoor pests | 0.838296 |
| cockroach infestation | 0.82906 |
| cockroach saliva | 0.88081 |
| individuals | 0.366925 |
| environmentally safe pesticides | 0.948285 |
| house | 0.399633 |
| cockroaches | 0.964162 |
| increases | 0.395672 |
| bait stations | 0.659522 |
|
| Recent studies | 0.703363 |
| presence | 0.375312 |
| older dwellings | 0.717387 |
| severity | 0.408653 |
| strong association | 0.705115 |
| neighborhoods | 0.393416 |
| garbage | 0.380996 |
| drain pipes | 0.670801 |
| urban areas | 0.672152 |
| dirty food | 0.661958 |
| allergens | 0.410573 |
| Mop | 0.395246 |
| spread | 0.36497 |
| bedrooms | 0.3934 |
| kitchen floor | 0.624146 |
| asthma symptoms | 0.714916 |
| Limit | 0.372106 |
|
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| 4175 |
National Institute of Environmental Health Sciences |
Html |
en |
Disruption and Homogenization of Tissue for the Extraction of RNA |
Disruption and Homogenization of Tissue for the Extraction of RNA |
| wet ice | 0.294869 |
| qiagen rneasyâ„¢ kit | 0.793299 |
| tissue | 0.953847 |
| optimal disruption | 0.413263 |
| new probe | 0.405893 |
| sterile water | 0.398045 |
| βME/RLT buffer | 0.416468 |
| homogenization | 0.341331 |
| saw tooth | 0.404319 |
| RLT buffer | 0.443007 |
| buffer | 0.45597 |
| ml | 0.269322 |
| steel rotor-stator generator | 0.389577 |
| sample cross contamination | 0.408302 |
| tissues | 0.250031 |
| dry ice | 0.301215 |
| weighed tissue | 0.518458 |
| excess RNAlaterâ„¢ | 0.297361 |
| oversized windows | 0.408273 |
| samples | 0.451817 |
| Omni Polytron | 0.308667 |
| tube | 0.458174 |
| intervals | 0.296602 |
| respective Qiagen RNeasyâ„¢ | 0.583744 |
| razor blades | 0.408361 |
|
| flat bottom tube | 0.34099 |
| disposable unit | 0.30983 |
| disposable probes | 0.399728 |
| medium-sized weigh boat | 0.385494 |
| better flow | 0.437073 |
| complete disruption | 0.526113 |
| small weigh boat | 0.374048 |
| Qiagen Rneasy kit | 0.398103 |
| minced sample | 0.387192 |
| http://www.qiagen.com/Products/Catalog/ | 0.304108 |
| speed | 0.372115 |
| appropriate volume | 0.405831 |
| lysis buffer | 0.444639 |
| final rinse | 0.31725 |
| high content | 0.307355 |
| fibrous tissue | 0.42298 |
| hand held unit | 0.405853 |
| saw tooth edge | 0.395095 |
| rotor-stator generator probes | 0.391962 |
| sample | 0.561073 |
| weigh boat | 0.409319 |
| probe | 0.792145 |
| timely manner | 0.309577 |
| rotor-stator generator probe | 0.661629 |
|
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| 4181 |
National Institute of Environmental Health Sciences |
Html |
en |
Cardiovascular Disease and Stroke |
Cardiovascular disease refers to a class of diseases that pertain to the heart of blood vessels, and is the leading cause of death in the United States. |
| coronary artery disease | 0.625439 |
| Lyme disease | 0.475226 |
| Extreme cold | 0.629318 |
| national mitigation strategy | 0.546097 |
| extreme weather events | 0.61312 |
| temperature extremes | 0.461159 |
| blood vessel dysfunction | 0.558794 |
| heart-related diseases | 0.479557 |
| pulmonary gas exchange | 0.578099 |
| novel fuels | 0.441058 |
| heart-related disorders | 0.483103 |
| fuel mixtures | 0.440747 |
| Human Health Perspective | 0.552703 |
| fossil fuel-based energy | 0.551119 |
| climate change | 0.555453 |
| greatest risk | 0.444161 |
| blood vessels | 0.455888 |
| potential health risks | 0.552162 |
| various cardiovascular disease | 0.708287 |
| ozone concentrations | 0.466831 |
| ozone formation | 0.460303 |
| alternative transportation options | 0.552334 |
| extreme heat increase | 0.622617 |
| cardiac dysrhythmias | 0.486275 |
|
| environmental exposures | 0.549621 |
| heart beat | 0.475 |
| systematic inflammation | 0.444794 |
| heart attacks | 0.585098 |
| heart attack | 0.47651 |
| United States | 0.463839 |
| Chagas disease | 0.483909 |
| complex synergistic effect | 0.546448 |
| cardiovascular health | 0.565248 |
| long-term climate change | 0.536049 |
| extreme heat | 0.758204 |
| hospital admissions | 0.733589 |
| Cardiovascular manifestations | 0.583257 |
| heart disease | 0.504885 |
| urban development | 0.439977 |
| pulmonary embolism | 0.459832 |
| cardiovascular disease | 0.930019 |
| heart function | 0.471543 |
| energy production activities | 0.551851 |
| cardiovascular diseases | 0.684271 |
| stroke | 0.465302 |
| zoonotic diseases | 0.460284 |
| chest pain | 0.444151 |
| stress-related cardiomyopathy | 0.456294 |
|
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| 4196 |
National Institute of Environmental Health Sciences |
Html |
en |
Obesogens |
Scientists are exploring the role that chemicals may play in weight gain and obesity. |
| endocrine disrupting chemicals | 0.770179 |
| lifespan | 0.34484 |
| fullness | 0.343842 |
| body | 0.416665 |
| general advice | 0.507905 |
| specific chemicals | 0.542695 |
| animals | 0.340365 |
| chemicals | 0.794503 |
| obesity | 0.979047 |
| cements | 0.341798 |
| liver disease | 0.485591 |
| endocrine disruptors | 0.792191 |
| hormones function | 0.54698 |
| normal metabolic processes | 0.691982 |
| fluorescent light ballasts | 0.667166 |
| fat cells | 0.661418 |
| Phthalates | 0.353836 |
| lack | 0.378184 |
| early development | 0.685447 |
| numerous grantees | 0.498784 |
| health problems | 0.491926 |
| broad class | 0.500556 |
| Scientists | 0.341058 |
| fetus | 0.340984 |
| NIEHS Obesity | 0.696031 |
|
| fat storage capacity | 0.695543 |
| role | 0.41859 |
| susceptibility | 0.403722 |
| sensitive time | 0.493095 |
| United States | 0.538956 |
| weight gain | 0.934543 |
| National Toxicology Program | 0.648859 |
| consumer products | 0.495976 |
| exercise | 0.368286 |
| obesogens | 0.524591 |
| Unhealthy diet | 0.525087 |
| industrial chemicals | 0.523316 |
| biphenyls | 0.349174 |
| related diseases | 0.486205 |
| cardiovascular disease | 0.487055 |
| obesity problem | 0.728164 |
| Diabetes program funds | 0.672946 |
| environmental chemicals | 0.521018 |
| healthy weight | 0.510655 |
| weight control mechanisms | 0.66665 |
| Poor nutrition | 0.508805 |
| high sugar diets | 0.658731 |
| exposures | 0.4701 |
| interfere | 0.353086 |
|
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| 4229 |
National Institute of Environmental Health Sciences |
Html |
en |
The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection |
Asthma patients seem to be more prone to viral infections, and NIEHS scientists believe that the cells that line these patients' airways, cause this result by overproducing TGF-beta1, a protein that promotes viral growth. |
| research team member | 0.420993 |
| North Carolina | 0.256008 |
| Non-smoking healthy adults | 0.41552 |
| final eligibility visit | 0.499939 |
| mild asthmatic participants | 0.793821 |
| medical history | 0.438584 |
| alveolar macrophages | 0.492495 |
| blood samples | 0.274456 |
| physical examination | 0.43791 |
| viral growth | 0.302566 |
| RSV infection | 0.525917 |
| NIEHS Clinical Research | 0.412814 |
| bronchoscopy | 0.334615 |
| viral infections | 0.311347 |
| inflammatory activity | 0.264911 |
| asthmatic epithelial susceptibility | 0.915952 |
| pulmonary function tests | 0.412673 |
| Asthma patients | 0.301404 |
| pulmonary function test | 0.434215 |
| contact Grace Isshiki | 0.414398 |
| vital signs | 0.262381 |
| airway cell samples | 0.469717 |
|
| blood draw | 0.261382 |
| NIEHS scientists | 0.334267 |
| pulmonary function | 0.448955 |
| study visit | 0.481064 |
| Trials Study page | 0.468853 |
| epithelial cells | 0.371544 |
| RSV infections | 0.358391 |
| primary objective | 0.257984 |
| medical history review | 0.403741 |
| asthmatic bronchial epithelia | 0.722628 |
| screening visit | 0.45057 |
| non-asthmatic participants | 0.357239 |
| Growth Factor-beta | 0.270314 |
| RSV replication | 0.353971 |
| controlled study | 0.29404 |
| Protocol Number | 0.268367 |
| Research Triangle Park | 0.38372 |
| laboratory analysis | 0.25923 |
| collect lung cells | 0.424885 |
| Potential participants | 0.355279 |
| normal epithelia | 0.491212 |
| respiratory syncytial virus | 0.419629 |
|
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| 16618 |
National Institute of Environmental Health Sciences |
Html |
en |
NIEHS-EPA Pilot Study of Exposure to Chemicals in Consumer Products |
In a lifetime, a person may encounter tens of thousands of chemicals used as ingredients in the products they buy. It’s not easy to measure these chemicals because the companies that sell the products aren’t required to divulge the exact chemical ingredients. |
| North Carolina | 0.560879 |
| tens | 0.383553 |
| data | 0.3493 |
| Sample collections | 0.563222 |
| methods | 0.350305 |
| household products | 0.605354 |
| lifetime | 0.363225 |
| surveys | 0.350222 |
| consumer products | 0.571843 |
| NIEHS Clinical Research | 0.798626 |
| Protocol number | 0.580892 |
| companies | 0.3538 |
| ways | 0.349382 |
| personal care | 0.601261 |
| contact | 0.349134 |
| studies | 0.349341 |
| definition | 0.346346 |
| measure exposure | 0.630122 |
|
| chemicals | 0.513973 |
| air samplers | 0.584149 |
| Volunteers | 0.348869 |
| models | 0.35018 |
| researcher | 0.411412 |
| chronic condition | 0.57685 |
| exact chemical ingredients | 0.925339 |
| Trials Study page | 0.846757 |
| control | 0.346765 |
| thousands | 0.352242 |
| 1-855-MYNIEHS | 0.346037 |
| normal activities | 0.594214 |
| home | 0.436662 |
| Researchers | 0.35043 |
| high blood pressure | 0.820406 |
| Research Triangle Park | 0.776504 |
| information | 0.393352 |
|
CLICK HERE |
| 16624 |
National Institute of Environmental Health Sciences |
Html |
en |
The NHALES Study: Natural History of Asthma with Longitudinal Environmental Sampling |
The goal of the NHALES Study is to help scientists understand how bacteria and other factors in the environment affect people who have moderate to severe asthma. |
| NHALES participants | 0.638974 |
| North Carolina | 0.507142 |
| stool | 0.402998 |
| medical history | 0.499342 |
| urine | 0.393797 |
| research study | 0.512378 |
| study doctor | 0.498489 |
| 5-year study | 0.540936 |
| house dust | 0.5025 |
| bronchoscopy procedure | 0.696031 |
| lungs | 0.340224 |
| NHALES visits | 0.666459 |
| biological sample | 0.47879 |
| Clinical Research Unit | 0.979253 |
| Sciences Clinical Research | 0.652184 |
| CRU visits | 0.737644 |
| asthma difficulties | 0.649747 |
| small group | 0.663031 |
| NHALES team members | 0.680144 |
| asthma medications | 0.739584 |
| scientists | 0.368565 |
| Research Triangle Park | 0.99468 |
| asthma consultations | 0.618544 |
| NHALES Study | 0.557965 |
| physical exams | 0.480592 |
|
| sputum | 0.364903 |
| NIEHS Clinical Research | 0.726739 |
| lung function testing | 0.639518 |
| adequate asthma treatment | 0.886905 |
| place | 0.366492 |
| health care | 0.492611 |
| National Institute | 0.488911 |
| participants | 0.730166 |
| breathing tests | 0.500855 |
| medical information | 0.480624 |
| eligible participants | 0.651078 |
| cost | 0.363023 |
| free doctor visits | 0.86146 |
| Trials Study page | 0.676238 |
| blood | 0.364975 |
| biological samples | 0.480007 |
| allergens | 0.339093 |
| saliva | 0.404633 |
| environment | 0.368403 |
| asthma control medications | 0.811738 |
| study visits | 0.627952 |
| asthma symptoms | 0.627078 |
| compensation | 0.353573 |
| time | 0.365125 |
|
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