| 4130 |
National Institute of Environmental Health Sciences |
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Dioxins |
Dioxins are mainly byproducts of industrial practices. They are produced through a variety of incineration processes, including improper municipal waste incineration and burning of trash, and can be released into the air during natural processes, such as forest fires and volcanoes. |
| major industrial sources | 0.618311 |
| particular animal products | 0.609962 |
| normal cell function | 0.581032 |
| ischemic heart disease | 0.59885 |
| human exposure | 0.529308 |
| health standards | 0.510938 |
| NIEHS researchers | 0.525543 |
| hazardous waste sites | 0.829585 |
| military service | 0.572111 |
| industrial practices | 0.523256 |
| dioxin releases | 0.752877 |
| acne-like skin disease | 0.595958 |
| Numerous dioxin-like compounds | 0.59691 |
| forest fires | 0.516286 |
| health problems | 0.509939 |
| singular term dioxin | 0.816081 |
| AhR receptor | 0.563591 |
| municipal waste incineration | 0.62579 |
| new industrial sources | 0.579948 |
| natural processes | 0.518596 |
| presumptive diseases | 0.570026 |
| worst hazardous waste | 0.582319 |
| food chain | 0.512812 |
| dioxin-like compounds | 0.618467 |
|
| United States | 0.509739 |
| dioxin contamination | 0.82313 |
| Polychlorinated Biphenyls | 0.652854 |
| incineration processes | 0.526748 |
| aryl hydrocarbon receptor | 0.591672 |
| dioxin emissions | 0.753553 |
| adverse health effects | 0.597235 |
| distinct chemical structures | 0.587839 |
| public health threats | 0.594166 |
| long time | 0.507128 |
| term dioxin | 0.841642 |
| environmental degradation | 0.512273 |
| Strict regulatory controls | 0.614092 |
| cancer-causing agent | 0.515417 |
| dioxin TCDD | 0.778376 |
| dioxin exposure | 0.792666 |
| dioxins | 0.916333 |
| dioxin | 0.96517 |
| major problem | 0.511605 |
| persistent organic pollutants | 0.595215 |
| Agent Orange | 0.63878 |
| electronic products | 0.512095 |
| dioxin damages | 0.726478 |
| living creature | 0.515875 |
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| 4154 |
National Institute of Environmental Health Sciences |
Html |
en |
Innate Immunity Signal Transduction in Human Leukocytes |
The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream. |
| blood cell function | 0.857637 |
| Innate Immunity Signal | 0.892013 |
| Recurrent fever | 0.691945 |
| research study | 0.739352 |
| participant | 0.580026 |
| Alcohol consumption | 0.680188 |
| white blood cells | 0.929239 |
| Blood pressure | 0.801272 |
| ml | 0.568081 |
| healthy adult donors | 0.845682 |
| Exposure Study | 0.739471 |
| Diarrhea | 0.538237 |
| Human Leukocytes | 0.724044 |
| dentist | 0.537883 |
| HMG CoA reductase | 0.857876 |
| BPA | 0.546679 |
| Insulin dependent diabetes | 0.82172 |
| CaREFREE Study | 0.753508 |
| Creutzfeldt-Jacob Disease | 0.671451 |
| Transduction | 0.541425 |
| lbs | 0.538272 |
| Calorie Restriction | 0.725628 |
| Ages Eligible | 0.706322 |
| Cox-2 Gene | 0.732119 |
|
| samples states | 0.670052 |
| Pulse rate | 0.661917 |
| suspected pregnancy | 0.691713 |
| Clinical Trials Study | 0.877316 |
| blood plasma | 0.738636 |
| corticosteroids | 0.544082 |
| inflammation | 0.538031 |
| cups | 0.554088 |
| possible disease-related conditions | 0.863689 |
| Bisphenol | 0.560014 |
| blood donation | 0.879466 |
| participants | 0.555679 |
| doctor visit | 0.690752 |
| bloodstream | 0.551006 |
| test tube | 0.68694 |
| substances | 0.570815 |
| Reproductive Effects | 0.70382 |
| immune cells | 0.891453 |
| antidepressants | 0.536599 |
| various signals | 0.700116 |
| Genders Eligible | 0.714599 |
| certain circumstances | 0.690168 |
| response | 0.580673 |
| antihistamines | 0.545714 |
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| 4155 |
National Institute of Environmental Health Sciences |
Html |
en |
Environmental Risk Factors for the Development of Myositis in Military Personnel |
This study attempts to determine if environmental and geographic exposures may be related to the development of myositis during military service and to obtain an initial understanding of the possible mechanisms involved. |
| health care provider | 0.681295 |
| chronic muscle disease | 0.93849 |
| physical examination | 0.481222 |
| safe blood | 0.346664 |
| normal volunteers | 0.349747 |
| case-control study | 0.351548 |
| study participation | 0.351448 |
| duty military personnel | 0.484031 |
| study kit | 0.351929 |
| blood draw | 0.453668 |
| Clinical Research Unit | 0.654948 |
| environmental factors | 0.337375 |
| autoimmune muscle disease | 0.462421 |
| healthy military personnel | 0.458188 |
| military service | 0.632731 |
| T.W. Alexander Drive | 0.425004 |
| Magnuson Clinical Center | 0.44092 |
| active duty personnel | 0.504103 |
| myositis subject | 0.545944 |
| Research Triangle Park | 0.658136 |
| environmental exposures | 0.564952 |
| blood samples | 0.484749 |
| Exclusion Criteria | 0.348534 |
| certain genetic factors | 0.423142 |
| NIEHS Clinical Research | 0.670167 |
|
| genetic factors | 0.442517 |
| genetically susceptible persons | 0.439463 |
| Clinical Trials Study | 0.518926 |
| military databases | 0.353364 |
| NIH Clinical Center | 0.659192 |
| myositis subjects | 0.662336 |
| Cognitive impairment | 0.338566 |
| inclusion criteria | 0.607689 |
| geographic exposures | 0.398012 |
| retrospective review | 0.341252 |
| active duty | 0.931322 |
| possible mechanisms | 0.350785 |
| previously approved studies | 0.433437 |
| occupational exposures | 0.367991 |
| contact study members | 0.441928 |
| questionnaires | 0.378349 |
| Matched Control Subjects | 0.524785 |
| single clinical visit | 0.438636 |
| local health care | 0.67535 |
| initial understanding | 0.351575 |
| clinical evaluations | 0.349061 |
| study investigators | 0.346145 |
| military experience | 0.371098 |
| military personnel | 0.680447 |
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| 4156 |
National Institute of Environmental Health Sciences |
Html |
en |
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study |
Bisphenol A (BPA) is a chemical that is used primarily to make plastics, resins, and thermal paper. |
| North Carolina | 0.404904 |
| resins | 0.235977 |
| medical history | 0.381623 |
| research study | 0.407097 |
| breastfeeding female | 0.395992 |
| low levels | 0.422271 |
| single oral dose | 0.577155 |
| Clinical Research Unit | 0.864438 |
| study period | 0.420853 |
| Regular blood samples | 0.562795 |
| volunteers | 0.234926 |
| water | 0.268032 |
| screening laboratory tests | 0.527317 |
| follow-up visit | 0.532141 |
| body absorbs | 0.401547 |
| BPA | 0.950847 |
| vanilla wafer cookie | 0.53318 |
| chemical | 0.238196 |
| Research Triangle Park | 0.877312 |
| BPA dose | 0.678802 |
| single dose | 0.599445 |
| 24-hour urine collections | 0.632026 |
| thermal paper | 0.423385 |
| CRU | 0.462451 |
|
| baby bottles | 0.417986 |
| effort | 0.258764 |
| Environmental Health Sciences | 0.535257 |
| additional blood | 0.384898 |
| NIEHS Clinical Research | 0.632204 |
| follow-up visits | 0.628047 |
| plastic products | 0.416823 |
| frequent blood tests | 0.533259 |
| place | 0.235059 |
| National Institute | 0.383375 |
| participants | 0.371129 |
| plastics | 0.238144 |
| reproductive age | 0.38114 |
| Trials Study page | 0.566642 |
| urine tests | 0.663008 |
| people | 0.237954 |
| food | 0.237865 |
| 13-hour visit | 0.506357 |
| Researchers | 0.237427 |
| study visits | 0.443822 |
| ages | 0.234675 |
| compensation | 0.25884 |
| BPA-containing products | 0.397451 |
| time | 0.321999 |
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| 4164 |
National Institute of Environmental Health Sciences |
Html |
en |
NIEHS Studies - Open for Recruitment |
NIEHS Studies - Open for Recruitment |
| Study The study | 0.446231 |
| Inflammatory Response | 0.444052 |
| Nicole Edwards | 0.882816 |
| Innate Immunity Signal | 0.437187 |
| Military Personnel Researchers | 0.44362 |
| Innate Immunity | 0.443622 |
| p53 Response Elements | 0.446014 |
| Healthy males | 0.441897 |
| Glucocorticoid Receptor SNPs | 0.440086 |
| body weight | 0.439072 |
| Sample Collection Registry | 0.436992 |
| RSV Infection NIEHS | 0.438836 |
| black cohosh | 0.503477 |
| autoimmune muscle disease | 0.44307 |
| Asthmatic Epithelial Cell | 0.440295 |
| Exposure Study | 0.440691 |
| Vessel Study Researchers | 0.457483 |
| Study Researchers | 0.488237 |
| suppressor gene p53 | 0.442725 |
| Cayden Maican | 0.441043 |
| chronic inflammatory disease | 0.441652 |
| Longitudinal Environmental Sampling | 0.439769 |
| NC | 0.505975 |
| Research Triangle Park | 0.989905 |
| NIEHS-EPA Pilot Study | 0.448482 |
|
| CaREFREE Study | 0.435439 |
| tobacco smoke exposure | 0.439481 |
| Smoking Study Researchers | 0.455683 |
| Psoriasis Study Researchers | 0.450501 |
| study | 0.491511 |
| mild asthmatic participants | 0.438227 |
| Natural History | 0.440486 |
| Metabolic Disease NIEHS | 0.444178 |
| people’s genes | 0.441006 |
| Inhaled Nanosilver Study | 0.454886 |
| Puberty Study Researchers | 0.459032 |
| Systemic Rheumatic Disorders | 0.441276 |
| chronic muscle weakness | 0.436267 |
| environmental risk factors | 0.526514 |
| rheumatic disease | 0.46918 |
| Environmental Polymorphisms Registry | 0.445136 |
| Adult-Onset Idiopathic Inflammatory | 0.440276 |
| factors Research Triangle | 0.480632 |
| females | 0.439464 |
| Black Cohosh Study | 0.473352 |
| healthy volunteers | 0.464562 |
| inhaled silver nanoparticles | 0.440803 |
| cox-2 gene | 0.439356 |
| military personnel | 0.450949 |
|
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| 4173 |
National Institute of Environmental Health Sciences |
Html |
en |
RNA Isolation from Pico-scale samples (1 cell (10-25pg) - 10mg tissue) with the PicoPure |
Protocol for Use with CapSure™ Macro LCM Caps; Protocol for Use with <10mg Frozen Tissue |
| precipitate | 0.343145 |
| pur. column/0.5ml tube | 0.567697 |
| maximum absorption | 0.429304 |
| membrane | 0.375077 |
| Pipette equal volume | 0.685863 |
| Incubate RT | 0.480046 |
| microcentrifuge tube cap | 0.562315 |
| I. Mix | 0.442745 |
| adjacent rotor holes | 0.540731 |
| 15 min | 0.600975 |
| EtOH mixture | 0.435111 |
| sec | 0.360753 |
| freeze cell extract | 0.563526 |
| min | 0.965686 |
| –80oC | 0.326544 |
| elution buffer | 0.45392 |
| store -20oC | 0.457309 |
| kit | 0.324004 |
| centrifuge assembly | 0.567112 |
| potential breakage | 0.429631 |
|
| EB | 0.389759 |
| wash buffer | 0.437578 |
| single-use aliquots | 0.465852 |
| waste | 0.324348 |
| Invert | 0.337448 |
| pre-conditioned purification column | 0.709665 |
| cell extract | 0.739782 |
| purification column | 0.840061 |
| stock solution | 0.457585 |
| column | 0.864391 |
| 42oC | 0.327805 |
| elution step | 0.451097 |
| Mix XB | 0.462681 |
| centrifugation | 0.373454 |
| clockwise direction | 0.445033 |
| centrifuge | 0.752672 |
| pipette | 0.80566 |
| W1 | 0.381424 |
| RNA isolation protocol | 0.571169 |
| W2 | 0.372703 |
|
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| 4183 |
National Institute of Environmental Health Sciences |
Html |
en |
Air Pollution |
Air pollution is a mixture of natural and man-made substances in the air we breathe. It is typically separated into two categories: outdoor air pollution and indoor air pollution. |
| Air grand prize | 0.402197 |
| landmark research project | 0.368948 |
| air pollution exposure. | 0.532873 |
| human health | 0.444187 |
| gulf oil spill | 0.384785 |
| Air Pollution Highlights | 0.498666 |
| Health Challenge | 0.367187 |
| national air quality | 0.417096 |
| new public health | 0.400982 |
| Human Health Perspective | 0.393804 |
| climate change | 0.544946 |
| air quality | 0.533929 |
| Pollution Exposure Response | 0.44974 |
| World Health Organization | 0.399338 |
| Air Pollution Declined | 0.497528 |
| portable air pollution | 0.508285 |
| air pollution research | 0.520586 |
| health effects. | 0.366189 |
| Traffic-Related Air Pollution | 0.4941 |
| NIEHS research efforts | 0.398851 |
| Air Quality Monitoring | 0.403077 |
| air pollution exposures | 0.521855 |
| Air Pollution Curbs | 0.492886 |
| India Research Goals | 0.366266 |
| Environmental Protection Agency | 0.469633 |
|
| health effects | 0.446311 |
| ADHD-Air Pollution Link | 0.451853 |
| health threats | 0.367517 |
| Environmental Public Health | 0.400619 |
| poor air quality | 0.415689 |
| daily Air Quality | 0.404172 |
| Human Health Effects | 0.396344 |
| Environmental Health Sciences | 0.393449 |
| U.S. Environmental Protection | 0.46905 |
| outdoor air pollution | 0.724933 |
| major public health | 0.390471 |
| indoor air pollution | 0.700415 |
| Major Global Health | 0.388329 |
| heart disease | 0.36867 |
| Air Quality Index | 0.455543 |
| Workshop Advances NIEHS | 0.397429 |
| public health | 0.44572 |
| NIEHS cookstove program | 0.400345 |
| Air Pollution Exposure | 0.514582 |
| next-generation air quality | 0.40097 |
| Air Pollution Pinpointed | 0.493631 |
| health | 0.469498 |
| public health problem | 0.390356 |
| air pollution | 0.960543 |
|
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| 4235 |
National Institute of Environmental Health Sciences |
Html |
en |
Pathogenic Studies in Families with Twins or Siblings Discordant for Systemic Rheumatic Disorders |
The goal of this study is to examine the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, when one has an autoimmune disease and the other does not. |
| daily occupation | 0.66172 |
| twin-sib pairs | 0.605567 |
| genetic risk factors | 0.611729 |
| environmental exposure questionnaires | 0.596699 |
| blood tests | 0.557539 |
| juvenile forms | 0.556664 |
| Idiopathic Thrombocytopenia Purpura | 0.603705 |
| single enrollment /evaluation | 0.603197 |
| Exclusion Criteria | 0.564799 |
| clinical evaluation | 0.560807 |
| same-sex siblings | 0.561544 |
| NIEHS Clinical Research | 0.599884 |
| possible causes | 0.559474 |
| normal volunteers | 0.602281 |
| clinical specimens | 0.557929 |
| Clinical Trials Study | 0.619818 |
| unaffected twin | 0.611768 |
| NIH Clinical Center | 0.596519 |
| environmental risk factors | 0.773866 |
| minimum inclusion criteria | 0.611286 |
| Systemic Lupus Erythematosus | 0.705107 |
| nonsteroidal anti-inflammatory drugs | 0.598992 |
| autoimmune diseases | 0.580697 |
|
| inclusion criteria | 0.638208 |
| risk factors | 0.841613 |
| severe trauma | 0.656995 |
| clinical care | 0.558499 |
| systemic rheumatic disorders | 0.958087 |
| Autoimmune Thyroid Disease | 0.620764 |
| T.W. Alexander Drive | 0.58526 |
| systemic rheumatic disease | 0.811247 |
| Systemic Vasculitis | 0.633034 |
| urine samples | 0.630701 |
| Magnuson Clinical Center | 0.597062 |
| autoimmune disease | 0.657433 |
| Active infections | 0.657042 |
| rheumatoid arthritis | 0.615934 |
| common clinical manifestations | 0.620645 |
| potential risk factors | 0.610009 |
| possible risk factors | 0.613252 |
| peripheral blood cell | 0.594747 |
| document medical histories | 0.586145 |
| chronic anti-inflammatory medicines | 0.595139 |
| Research Triangle Park | 0.584599 |
| systemic rheumatic disorder | 0.726613 |
|
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| 16602 |
National Institute of Environmental Health Sciences |
Html |
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Soy Infant Formula |
Soy formula is an infant food made using soy protein and other components. It is fed to infants as a supplement or replacement for human milk or cow milk formula. |
| soy exposure levels | 0.424682 |
| American Academy | 0.286003 |
| NTP conclusions | 0.282831 |
| cow milk formula | 0.416842 |
| Lactose-free cow milk | 0.288905 |
| concern levels | 0.273187 |
| panel’s conclusions | 0.256675 |
| soy foods | 0.37521 |
| NTP panel | 0.272404 |
| amino acid formulations | 0.280665 |
| case soy infant | 0.513993 |
| soy infant formula | 0.90079 |
| infant food | 0.307478 |
| relatively large number | 0.272799 |
| soy supplements | 0.374399 |
| public health decisions | 0.275387 |
| estrogen-like effects | 0.285283 |
| infants | 0.425564 |
| soy protein-based formula | 0.523072 |
| specific health problems | 0.287669 |
| percent decrease | 0.257771 |
| appropriate regulatory authorities | 0.269886 |
| infant nutrition | 0.292621 |
| adverse human health | 0.341425 |
| adverse effects | 0.246835 |
|
| developmental stages | 0.283925 |
| health effects | 0.27525 |
| cow milk-based formula | 0.381713 |
| human infants | 0.298676 |
| infant formula sales | 0.423073 |
| amino acids | 0.287446 |
| total dollar sales | 0.274341 |
| human milk | 0.292218 |
| five-level scale | 0.279285 |
| NTP | 0.295344 |
| formula-fed infants | 0.286235 |
| Soy Protein-Based Formulas | 0.417913 |
| soy formula | 0.864282 |
| minimal concern | 0.280528 |
| soy milk | 0.414438 |
| possible concern | 0.250753 |
| soy products | 0.404294 |
| adverse developmental effects | 0.277138 |
| breast milk | 0.246481 |
| current infant formulas | 0.330619 |
| primary isoflavones | 0.267607 |
| clinical report states | 0.277267 |
| Infant Feeding | 0.289819 |
| expert panel | 0.319558 |
|
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| 16622 |
National Institute of Environmental Health Sciences |
Html |
en |
The CaREFREE Study: Calorie Restriction, Environment, and Fitness: Reproductive Effects Evaluation |
Many women develop irregular menstrual cycles which may make it difficult to become pregnant and increase the risk of osteoporosis. |
| North Carolina | 0.687285 |
| exercise plan | 0.590059 |
| following criteria | 0.548071 |
| research study | 0.549491 |
| Procedures | 0.342664 |
| Participants | 0.665485 |
| body | 0.342491 |
| blood sampling | 0.550047 |
| home blood | 0.549715 |
| 5-day exercise | 0.634228 |
| study steps | 0.554547 |
| birth | 0.343855 |
| 9-10 | 0.343397 |
| weight | 0.343026 |
| diet regimens | 0.578226 |
| consecutive menstrual cycles | 0.870958 |
| carefree@mail.nih.gov. | 0.547487 |
| osteoporosis | 0.354801 |
| planning | 0.340911 |
| fitness testing | 0.555107 |
| Protocol Number | 0.540756 |
| Research Triangle Park | 0.71823 |
| effect | 0.345611 |
| women | 0.433121 |
| physical exams | 0.532585 |
|
| irregular menstrual cycles | 0.918449 |
| UNC | 0.348875 |
| NIEHS Clinical Research | 0.735764 |
| reproductive cycles | 0.614837 |
| nutritional shakes | 0.549198 |
| measurement | 0.342523 |
| cookies | 0.340846 |
| duration | 0.351285 |
| visits | 0.343136 |
| ovulation tests | 0.548547 |
| charge | 0.340617 |
| bone density | 0.554919 |
| Trials Study page | 0.779331 |
| Parking | 0.339602 |
| urine tests | 0.588417 |
| Chapel Hill | 0.528804 |
| transportation | 0.339855 |
| meal | 0.341798 |
| environment | 0.346253 |
| information | 0.380051 |
| risk | 0.347239 |
| breastfeeding | 0.350001 |
| time | 0.344163 |
| visit | 0.342012 |
|
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