| 4154 |
National Institute of Environmental Health Sciences |
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en |
Innate Immunity Signal Transduction in Human Leukocytes |
The Innate Immunity Signal Transduction in Human Leukocytes is a research study to determine the response of immune cells from the bloodstream. |
| blood cell function | 0.857637 |
| Innate Immunity Signal | 0.892013 |
| Recurrent fever | 0.691945 |
| research study | 0.739352 |
| participant | 0.580026 |
| Alcohol consumption | 0.680188 |
| white blood cells | 0.929239 |
| Blood pressure | 0.801272 |
| ml | 0.568081 |
| healthy adult donors | 0.845682 |
| Exposure Study | 0.739471 |
| Diarrhea | 0.538237 |
| Human Leukocytes | 0.724044 |
| dentist | 0.537883 |
| HMG CoA reductase | 0.857876 |
| BPA | 0.546679 |
| Insulin dependent diabetes | 0.82172 |
| CaREFREE Study | 0.753508 |
| Creutzfeldt-Jacob Disease | 0.671451 |
| Transduction | 0.541425 |
| lbs | 0.538272 |
| Calorie Restriction | 0.725628 |
| Ages Eligible | 0.706322 |
| Cox-2 Gene | 0.732119 |
|
| samples states | 0.670052 |
| Pulse rate | 0.661917 |
| suspected pregnancy | 0.691713 |
| Clinical Trials Study | 0.877316 |
| blood plasma | 0.738636 |
| corticosteroids | 0.544082 |
| inflammation | 0.538031 |
| cups | 0.554088 |
| possible disease-related conditions | 0.863689 |
| Bisphenol | 0.560014 |
| blood donation | 0.879466 |
| participants | 0.555679 |
| doctor visit | 0.690752 |
| bloodstream | 0.551006 |
| test tube | 0.68694 |
| substances | 0.570815 |
| Reproductive Effects | 0.70382 |
| immune cells | 0.891453 |
| antidepressants | 0.536599 |
| various signals | 0.700116 |
| Genders Eligible | 0.714599 |
| certain circumstances | 0.690168 |
| response | 0.580673 |
| antihistamines | 0.545714 |
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| 4156 |
National Institute of Environmental Health Sciences |
Html |
en |
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study |
Bisphenol A (BPA) is a chemical that is used primarily to make plastics, resins, and thermal paper. |
| North Carolina | 0.404904 |
| resins | 0.235977 |
| medical history | 0.381623 |
| research study | 0.407097 |
| breastfeeding female | 0.395992 |
| low levels | 0.422271 |
| single oral dose | 0.577155 |
| Clinical Research Unit | 0.864438 |
| study period | 0.420853 |
| Regular blood samples | 0.562795 |
| volunteers | 0.234926 |
| water | 0.268032 |
| screening laboratory tests | 0.527317 |
| follow-up visit | 0.532141 |
| body absorbs | 0.401547 |
| BPA | 0.950847 |
| vanilla wafer cookie | 0.53318 |
| chemical | 0.238196 |
| Research Triangle Park | 0.877312 |
| BPA dose | 0.678802 |
| single dose | 0.599445 |
| 24-hour urine collections | 0.632026 |
| thermal paper | 0.423385 |
| CRU | 0.462451 |
|
| baby bottles | 0.417986 |
| effort | 0.258764 |
| Environmental Health Sciences | 0.535257 |
| additional blood | 0.384898 |
| NIEHS Clinical Research | 0.632204 |
| follow-up visits | 0.628047 |
| plastic products | 0.416823 |
| frequent blood tests | 0.533259 |
| place | 0.235059 |
| National Institute | 0.383375 |
| participants | 0.371129 |
| plastics | 0.238144 |
| reproductive age | 0.38114 |
| Trials Study page | 0.566642 |
| urine tests | 0.663008 |
| people | 0.237954 |
| food | 0.237865 |
| 13-hour visit | 0.506357 |
| Researchers | 0.237427 |
| study visits | 0.443822 |
| ages | 0.234675 |
| compensation | 0.25884 |
| BPA-containing products | 0.397451 |
| time | 0.321999 |
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| 4157 |
National Institute of Environmental Health Sciences |
Html |
en |
Blood Vessel Study |
The endothelium is the inner lining of blood vessels. The cells in this lining help regulate blood flow and immune system function. |
| North Carolina | 0.593975 |
| certain diseases | 0.51467 |
| medical history | 0.592865 |
| Sample collections | 0.495826 |
| arteries | 0.42047 |
| research study | 0.513955 |
| Participants | 0.488437 |
| certain genes | 0.626794 |
| electrocardiogram | 0.425687 |
| informed consent | 0.506292 |
| genetic risk | 0.505664 |
| blood flow | 0.602203 |
| contact Grace Isshiki | 0.583686 |
| endothelial function | 0.644334 |
| single study visit | 0.622939 |
| Clinical Research Unit | 0.904054 |
| Sciences Clinical Research | 0.585233 |
| blood vessels | 0.593264 |
| urine samples | 0.514808 |
| artery | 0.445869 |
| Protocol Number | 0.496279 |
| Research Triangle Park | 0.923425 |
| inner lining | 0.614816 |
| problems | 0.433444 |
| immune system function | 0.514997 |
|
| endothelial cells | 0.557885 |
| healthy adults | 0.503616 |
| short-acting dose | 0.494919 |
| blood samples | 0.503224 |
| CRU | 0.449371 |
| short-acting medication | 0.499172 |
| NIEHS Clinical Research | 0.776132 |
| protocol procedures | 0.497126 |
| Clinical Trials Study | 0.600871 |
| study procedures | 0.506002 |
| current participant | 0.501346 |
| nitroglycerin | 0.442508 |
| heart disease | 0.514134 |
| Environmental Polymorphisms Registry | 0.586863 |
| place | 0.433692 |
| arm | 0.436358 |
| National Institute | 0.496202 |
| endothelium | 0.431348 |
| ultrasound | 0.436314 |
| high blood pressure | 0.619133 |
| information | 0.466386 |
| compensation | 0.428407 |
| time | 0.433266 |
| physical exam | 0.59612 |
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| 4168 |
National Institute of Environmental Health Sciences |
Html |
en |
Dust Mites |
Dust mites are tiny microscopic relatives of the spider and live on mattresses, bedding, upholstered furniture, carpets and curtains. |
| mattress | 0.526228 |
| wool | 0.523488 |
| wall-to-wall carpets | 0.642846 |
| washable ones | 0.645538 |
| skin | 0.527373 |
| mattresses | 0.532003 |
| Non-washable bedding | 0.678267 |
| matter | 0.524449 |
| vacuumed area | 0.650761 |
| number | 0.526098 |
| bedding | 0.702029 |
| furniture | 0.551099 |
| HEPA filter | 0.642721 |
| air conditioner | 0.654009 |
| rag | 0.529546 |
| hot water | 0.64014 |
| fabric curtains | 0.635241 |
| mask | 0.525356 |
| double-layered microfilter bag | 0.747335 |
| damp mop | 0.653045 |
| allergen impermeable covers | 0.792903 |
|
| relative humidity | 0.651485 |
| dust mites | 0.927689 |
| mite allergens | 0.698748 |
| humid environments | 0.674421 |
| department stores | 0.639186 |
| relatives | 0.531428 |
| people | 0.527351 |
| home | 0.525607 |
| bedrooms | 0.531518 |
| dry cloth | 0.627517 |
| order companies | 0.642268 |
| flakes | 0.537114 |
| bare floors | 0.640016 |
| dehumidifier | 0.544992 |
| pillows | 0.524598 |
| synthetic materials | 0.633888 |
| suggestions | 0.524179 |
| specialty supply mail | 0.760387 |
| spider | 0.528169 |
| tiny creatures | 0.667074 |
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| 4206 |
National Institute of Environmental Health Sciences |
Html |
en |
Disaster Research Response Efforts |
The National Institute of Environmental Health Sciences, and other agencies that make up the Department of Health and Human Services (HHS) are set up to immediately respond and protect the health of our nation during disasters and other emergencies. |
| general public | 0.563696 |
| virus transmission | 0.549613 |
| Human Services | 0.605181 |
| health research | 0.846428 |
| health information | 0.617147 |
| program | 0.453475 |
| research protocols | 0.602746 |
| Hurricanes Katrina | 0.578453 |
| emergencies | 0.434027 |
| Department | 0.43094 |
| World Trade Center | 0.721562 |
| Research Priorities | 0.595232 |
| data needs | 0.588403 |
| HHS agencies | 0.61918 |
| timely human health | 0.787715 |
| additional accurate information | 0.680677 |
| disasters | 0.526256 |
| timely collection | 0.613439 |
| toxicology data | 0.577406 |
| research issues | 0.598483 |
| public health officials | 0.736737 |
| ready-to-go research data | 0.782213 |
| ongoing activities | 0.553892 |
| private sector | 0.552701 |
| Gulf oil spill | 0.715572 |
|
| important area | 0.562187 |
| emergency responders | 0.588812 |
| real-world conditions | 0.559721 |
| appropriate measures | 0.548422 |
| Building | 0.427956 |
| critical health research | 0.82695 |
| Public Health Research | 0.795376 |
| difficult circumstances | 0.579179 |
| Disaster Research Response | 0.82355 |
| Environmental Health Sciences | 0.960768 |
| highlights recent discussions | 0.687513 |
| IOM report | 0.604329 |
| non-governmental organizations | 0.561841 |
| Ebola Virus Disease | 0.698118 |
| timely gathering | 0.602838 |
| National Library | 0.578103 |
| collection tools | 0.570209 |
| human data | 0.592395 |
| National Institute | 0.744163 |
| Medical Practice | 0.55662 |
| previous disaster response | 0.790536 |
| NIH | 0.4312 |
| Medicine | 0.452613 |
| Inform Public Health | 0.745233 |
|
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| 4229 |
National Institute of Environmental Health Sciences |
Html |
en |
The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection |
Asthma patients seem to be more prone to viral infections, and NIEHS scientists believe that the cells that line these patients' airways, cause this result by overproducing TGF-beta1, a protein that promotes viral growth. |
| research team member | 0.420993 |
| North Carolina | 0.256008 |
| Non-smoking healthy adults | 0.41552 |
| final eligibility visit | 0.499939 |
| mild asthmatic participants | 0.793821 |
| medical history | 0.438584 |
| alveolar macrophages | 0.492495 |
| blood samples | 0.274456 |
| physical examination | 0.43791 |
| viral growth | 0.302566 |
| RSV infection | 0.525917 |
| NIEHS Clinical Research | 0.412814 |
| bronchoscopy | 0.334615 |
| viral infections | 0.311347 |
| inflammatory activity | 0.264911 |
| asthmatic epithelial susceptibility | 0.915952 |
| pulmonary function tests | 0.412673 |
| Asthma patients | 0.301404 |
| pulmonary function test | 0.434215 |
| contact Grace Isshiki | 0.414398 |
| vital signs | 0.262381 |
| airway cell samples | 0.469717 |
|
| blood draw | 0.261382 |
| NIEHS scientists | 0.334267 |
| pulmonary function | 0.448955 |
| study visit | 0.481064 |
| Trials Study page | 0.468853 |
| epithelial cells | 0.371544 |
| RSV infections | 0.358391 |
| primary objective | 0.257984 |
| medical history review | 0.403741 |
| asthmatic bronchial epithelia | 0.722628 |
| screening visit | 0.45057 |
| non-asthmatic participants | 0.357239 |
| Growth Factor-beta | 0.270314 |
| RSV replication | 0.353971 |
| controlled study | 0.29404 |
| Protocol Number | 0.268367 |
| Research Triangle Park | 0.38372 |
| laboratory analysis | 0.25923 |
| collect lung cells | 0.424885 |
| Potential participants | 0.355279 |
| normal epithelia | 0.491212 |
| respiratory syncytial virus | 0.419629 |
|
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| 15753 |
National Institute of Environmental Health Sciences |
Html |
en |
Harmful Algal Blooms |
A harmful algal bloom (HAB) occurs when toxin-producing algae grow excessively in a body of water. Algae are microscopic organisms that live in aquatic environments and use photosynthesis to produce energy from sunlight, just like plants. The excessive algal growth, or algal bloom, becomes visible to the naked eye and can be green, blue-green, red, or brown, depending on the type of algae. |
| neurotoxic domoic acid | 0.392745 |
| airborne toxins | 0.3579 |
| term health effects | 0.420968 |
| economic impacts | 0.377574 |
| common HABs | 0.602634 |
| harmful algal bloom | 0.492829 |
| recreational areas | 0.380488 |
| HABs | 0.943382 |
| NIEHS support | 0.379446 |
| human health | 0.572242 |
| state health officials | 0.406098 |
| regional HAB forecasts | 0.413664 |
| organism Karenia brevis | 0.361003 |
| Alexandrium fundyense bloom | 0.385445 |
| short term memory | 0.376589 |
| internal annual clock | 0.353558 |
| low level exposures | 0.374403 |
| HAB toxins | 0.604331 |
| public health officials | 0.38403 |
| domoic acid | 0.507804 |
| scientists | 0.351778 |
| NIEHS-funded Woods Hole | 0.379458 |
| health effects | 0.537186 |
| toxin-producing algae | 0.364296 |
| excessive algal growth | 0.456116 |
|
| Hole Oceanographic Institution | 0.483141 |
| Environmental Sample Processor | 0.643362 |
| HAB-related toxins | 0.384227 |
| paralytic shellfish poisoning | 0.375066 |
| long term effects | 0.382896 |
| recreationally caught seafood | 0.387875 |
| Woods Hole Center | 0.81038 |
| Administration studies HABs | 0.646677 |
| cystic fibrosis | 0.352577 |
| water treatment plants | 0.395893 |
| minimal economic impacts | 0.355742 |
| harmful algal blooms | 0.446013 |
| public health | 0.386735 |
| local health advisories | 0.410462 |
| remotely test seawater | 0.360093 |
| Human Health Program | 0.402242 |
| low level exposure | 0.361971 |
| Woods Hole Oceanographic | 0.488629 |
| drinking water sources | 0.56797 |
| Human Health. | 0.359967 |
| algae Alexandrium fundyense | 0.40309 |
| time damages brain | 0.364207 |
| warmer water temperatures | 0.423583 |
| low level | 0.381333 |
|
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| 16603 |
National Institute of Environmental Health Sciences |
Html |
en |
Program Announcements |
null |
| Predoctoral Dual-Degree Training | 0.408499 |
| Innovative Basic Research | 0.43641 |
| Institutional Predoctoral Dual-Degree | 0.401 |
| Career Development Award | 0.438479 |
| Institutional Research Training | 0.490585 |
| Clinical Scientist Research | 0.463378 |
| R21 Clinical Trial | 0.790332 |
| Lasker Clinical Research | 0.431211 |
| Genomics Research Project | 0.400975 |
| Ruth L. Kirschstein | 0.91615 |
| Admin Supp | 0.644561 |
| R21 Clinical Trials | 0.50727 |
| Kirschstein National Research | 0.919201 |
| NIH Small Research | 0.469875 |
| Research Career Development | 0.502582 |
| PA-16-288 Research Supplements | 0.404228 |
| Individual Predoctoral Fellowship | 0.426438 |
| Research Advancement Award | 0.424988 |
| Research Service Award | 0.906555 |
| Mentored Patient-Oriented Research | 0.444278 |
| CDC Translational Research | 0.402165 |
| Collaborative Minority Health | 0.398775 |
| Research Training Grant | 0.51904 |
| Parent R01 Clinical | 0.689624 |
|
| Research Cooperative Program | 0.410182 |
| Environmental Health Research | 0.492867 |
| National Research Service | 0.919142 |
| Research Grant Applications | 0.437245 |
| Clinical Trial Required | 0.4427 |
| Native American Health | 0.40952 |
| Summer Research Experiences | 0.43318 |
| Cancer Development Later | 0.424588 |
| Autism Spectrum Disorders | 0.42177 |
| L. Kirschstein National | 0.909899 |
| Clinical Trial Optional | 0.743266 |
| NIH Research Project | 0.568383 |
| R01 Clinical Trial | 0.951463 |
| PA-16-289 Research Supplements | 0.403662 |
| NIH Exploratory/Developmental Research | 0.569902 |
| Health Disparities Research | 0.50693 |
| Parent R21 Clinical | 0.663051 |
| Exploratory/Developmental Research Grant | 0.667354 |
| Short-Term Institutional Research | 0.402961 |
| Research Grant Program | 0.724194 |
| Research Project Grant | 0.617972 |
| Addressing Health Disparities | 0.425587 |
| Genomics Exploratory/Developmental Research | 0.449712 |
| Research Development Award | 0.475051 |
|
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| 16604 |
National Institute of Environmental Health Sciences |
Html |
en |
Request for Applications |
null |
| Complex Disease Outcomes | 0.44269 |
| Neuroscience Research | 0.342499 |
| New Investigators | 0.314504 |
| OD-17-013 Tobacco Regulatory | 0.4289 |
| CNS Small Blood | 0.600042 |
| R21 | 0.282735 |
| Creating Virtual Consortium | 0.424251 |
| Innovative Approaches | 0.317484 |
| Cancer Immunoprevention Research | 0.448358 |
| R24 | 0.243887 |
| Translational/Transdisciplinary Environmental Research | 0.487286 |
| New Environmental Scientist | 0.680923 |
| Immuno-Oncology Translation Network | 0.57748 |
| Model Organism Research | 0.470987 |
| EHS CC | 0.334179 |
| NIH Revision Awards | 0.474345 |
| Research Projects | 0.411478 |
| Environmental Epidemiology Cohorts | 0.500616 |
| AA-18-007 NIH Blueprint | 0.459649 |
| OD-17-014 Tobacco Regulatory | 0.42655 |
| Toxicology Testing | 0.319043 |
| Chemical Toxicity Screening | 0.42975 |
| Trial Not Allowed | 0.332615 |
| Outstanding New Environmental | 0.686 |
| Target Identification | 0.307541 |
|
| Reduce Animal | 0.314027 |
| NS-18-007 NIH Blueprint | 0.471778 |
| Organotypic Culture Models | 0.436552 |
| Cancer Immunotherapy Research | 0.455365 |
| SBIR Phase IIB | 0.451033 |
| Functional Heterogeneity | 0.329198 |
| Enrich Resource Infrastructure | 0.452224 |
| Environmental Health Sciences | 0.653664 |
| Regulatory Science Small | 0.424889 |
| Lymphatic Vessels | 0.416025 |
| Grant Program | 0.302409 |
| Disease Mechanisms Specific | 0.405835 |
| Experimental Animals | 0.328151 |
| Tobacco Regulatory Science | 0.690892 |
| Clinical Trial Optional | 0.46297 |
| ONES | 0.24071 |
| ES-17-003 Environmental Health | 0.466505 |
| R01 Clinical Trial | 0.9507 |
| Time-Sensitive Research Opportunities | 0.466832 |
| Dynamic Neuroimmune Interactions | 0.416097 |
| Sciences Core Centers | 0.437108 |
| Diversity Specialized Predoctoral | 0.419143 |
| Human Studies | 0.312119 |
| Postdoctoral Advancement | 0.314025 |
|
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| 16614 |
National Institute of Environmental Health Sciences |
Html |
en |
Body Weight & Puberty Study |
Over the past decade, there has been an alarming trend toward earlier breast development in girls. There have been some recent reports that overweight girls are developing breast tissue earlier than normal weight girls. |
| NIEHS CRU | 0.533534 |
| North Carolina | 0.494434 |
| breast ultrasound | 0.540589 |
| pelvic) ultrasounds. | 0.576093 |
| questions | 0.432669 |
| rewarding experience | 0.484692 |
| body composition | 0.576901 |
| face barriers | 0.482268 |
| following procedures | 0.564966 |
| state-of-the-art pediatric medicine | 0.557083 |
| pubertal development | 0.494411 |
| previous studies | 0.498655 |
| nearby Wake Radiology | 0.914448 |
| chest | 0.440567 |
| Clinical Research Unit | 0.719069 |
| hand x-ray | 0.49161 |
| better job | 0.496952 |
| time frame | 0.485793 |
| reproductive hormones | 0.486246 |
| recent reports | 0.503639 |
| travel costs | 0.572785 |
| comprehensive physical exam | 0.555799 |
| Research Triangle Park | 0.570505 |
| fatty tissue | 0.642042 |
| normal weight girls | 0.756039 |
|
| alarming trend | 0.510728 |
| Parents/Legal Guardians | 0.4913 |
| NIEHS Clinical Research | 0.746024 |
| young age | 0.482797 |
| study procedures | 0.567037 |
| breast tissue | 0.824644 |
| parent/legal guardian | 0.481978 |
| place | 0.430164 |
| his/her daughter | 0.496353 |
| Trials Study page | 0.584561 |
| study visit | 0.508894 |
| permission | 0.437351 |
| urine tests | 0.496238 |
| normal activities | 0.50132 |
| legal guardians | 0.497245 |
| wake radiology center | 0.90581 |
| overweight girls | 0.8371 |
| study site | 0.500971 |
| study visits | 0.662097 |
| bone age | 0.489503 |
| early puberty | 0.518116 |
| physical exam | 0.577111 |
| overweight girl | 0.544754 |
| past decade | 0.506031 |
|
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