| 1355 |
National Cancer Institute |
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Rectal Cancer Treatment (PDQ®)–Health Professional Version |
Expert-reviewed information summary about the treatment of rectal cancer. |
| metastatic colorectal carcinoma | 0.354846 |
| hepatic colorectal metastases | 0.223514 |
| recurrent rectal cancer | 0.223407 |
| Engl J Med | 0.263348 |
| Ann Surg | 0.278325 |
| colorectal cancer risk | 0.276481 |
| asymptomatic colorectal cancer | 0.241606 |
| colorectal cancer surgery | 0.262375 |
| metastatic colorectal cancer | 0.610251 |
| adjuvant rectal cancer | 0.215149 |
| colorectal cancer | 0.902264 |
| randomized trial | 0.206269 |
| patients | 0.22566 |
| progressive colorectal cancer | 0.233252 |
| pT3-pT4 colorectal cancer | 0.254826 |
| Clin Cancer Res | 0.224834 |
| refractory metastatic colorectal | 0.227594 |
| malignant colorectal adenomas | 0.207762 |
| et al. | 0.485182 |
| familial colorectal cancer | 0.266438 |
| colorectal liver metastases | 0.255119 |
| measurable colorectal cancer | 0.232282 |
| Dis Colon Rectum | 0.282416 |
| PUBMED Abstract | 0.3294 |
|
| untreated metastatic colorectal | 0.230109 |
| colorectal hepatic metastases | 0.221405 |
| advanced colorectal cancer | 0.352094 |
| irinotecan-refractory metastatic colorectal | 0.231657 |
| Colorectal lung metastases | 0.222615 |
| advanced colorectal carcinoma | 0.23983 |
| recurrent colorectal cancer | 0.262817 |
| Surg Oncol | 0.226556 |
| colorectal cancer incidence | 0.264939 |
| colorectal cancer present | 0.264636 |
| colorectal cancer disparities | 0.265307 |
| colorectal cancer group | 0.277657 |
| colorectal cancer rates | 0.265187 |
| Colorectal Study Group | 0.21517 |
| Abstract | 0.47664 |
| colon cancer | 0.223051 |
| Clin Oncol | 0.752938 |
| Colorectal cancer follow-up | 0.250811 |
| liver-limited metastatic colorectal | 0.225511 |
| Oncol Biol Phys | 0.206575 |
| dutch colorectal cancer | 0.274376 |
| Clin Colorectal Cancer | 0.277838 |
| Cancer J Clin | 0.227264 |
| colorectal carcinoma metastases | 0.224249 |
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| 1369 |
National Cancer Institute |
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en |
Oral Cavity and Oropharyngeal Cancer Screening (PDQ®)–Health Professional Version |
Expert-reviewed information summary about tests used to detect or screen for oral cancer. |
| oral examination | 0.527557 |
| primary screening tool | 0.417249 |
| squamous cell tumors. | 0.370971 |
| one-time oral cancer | 0.520022 |
| systematic oral cavity | 0.508919 |
| United States | 0.382344 |
| follow-up period | 0.371029 |
| sole randomized trial | 0.365707 |
| physical examination | 0.446254 |
| cause-specific mortality benefit | 0.39145 |
| opportunistic screening | 0.371936 |
| control group | 0.369767 |
| short follow-up period | 0.359545 |
| earlier stage cancers | 0.419364 |
| randomized controlled trials | 0.375895 |
| oral visual screening | 0.601987 |
| simple hand-held device | 0.363139 |
| oral cancer mortality | 0.59501 |
| premalignant lesions | 0.420448 |
| oral visual examination | 0.580404 |
| premalignant oral lesions. | 0.561468 |
| statistically significant result | 0.355967 |
| toluidine blue staining | 0.36957 |
| direct fluorescence visualization | 0.371807 |
|
| blue placebo dye. | 0.359062 |
| oral cancer | 0.97737 |
| oral/pharyngeal cancers | 0.364948 |
| oral surgery | 0.457512 |
| oral cancers | 0.781555 |
| 15-year follow-up period | 0.369337 |
| overall annual incidence | 0.409124 |
| overall oral cancers | 0.566597 |
| routine examination | 0.355451 |
| screening group | 0.361703 |
| subclinical high-risk fields | 0.375561 |
| oral cancer examination. | 0.562099 |
| positive predictive values | 0.349612 |
| mortality hazard ratios | 0.399552 |
| population-based screening programs | 0.456558 |
| better health outcomes. | 0.355075 |
| oral cavity | 0.532106 |
| positive test rates | 0.356123 |
| periodic health examination | 0.447578 |
| oral cancer examination | 0.728118 |
| screening setting | 0.362271 |
| screening rounds | 0.355833 |
| cause–specific mortality rate | 0.408751 |
|
CLICK HERE |
| 1770 |
National Cancer Institute |
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es |
Prurito (PDQ®)–Versión para profesionales de salud |
Resumen de información revisada por expertos acerca del prurito (picazón en la piel) como complicación del cáncer o su tratamiento. Se consideran los abordajes de manejo y tratamiento del prurito. |
| haemodialysis patients | 0.476654 |
| Section XII | 0.477073 |
| Rubenstein E | 0.559292 |
| Sin embargo | 0.803552 |
| Scientific American Medicine | 0.676981 |
| categorÃa farmacológica medicamento | 0.526417 |
| Am Acad Dermatol | 0.571569 |
| Clin Res | 0.479277 |
| Wolff K | 0.536775 |
| Acad Dermatol Venereol | 0.493209 |
| Farber EM | 0.55456 |
| patients with atopic | 0.550773 |
| Cancer Nursing | 0.471101 |
| PDQ Prurito | 0.665745 |
| Dermatol Venereol Leprol | 0.6251 |
| with atopic dermatitis | 0.566467 |
| toxina botulÃnica | 0.473345 |
| reacciones cutáneas | 0.538217 |
| patients with | 0.621762 |
| chronic idiopathic | 0.533598 |
| Pain Symptom Manage | 0.649291 |
| neuropathic pruritus | 0.513717 |
| Scientific American | 0.875762 |
| Oncol Nurs Forum | 0.782558 |
| Malignant cutaneous tumors | 0.546882 |
|
| Dosis Comentarios Referencias | 0.53479 |
| General Medicine | 0.52531 |
| terminal cancer patient | 0.535978 |
| All Free Clear | 0.515267 |
| Dermatol Venereol | 0.632286 |
| farmacológica medicamento dosis | 0.550466 |
| Clinical aspects | 0.477546 |
| Medicamento Dosis Comentarios | 0.541353 |
| Acta Derm Venereol | 0.979711 |
| Eisen AZ | 0.543793 |
| New York | 0.832579 |
| patients receiving | 0.483634 |
| Yosipovitch G | 0.516371 |
| mg diarios comenzar | 0.507465 |
| Abel EA | 0.553787 |
| Enterostomal Ther | 0.474722 |
| sistema nervioso central | 0.522009 |
| pruritus relief with | 0.489446 |
| policitemia vera | 0.673444 |
| Dermatol Ther | 0.602936 |
| Fitzpatrick TB | 0.546636 |
| Federman DD | 0.567864 |
| Bernhard JD | 0.556935 |
| chronic pruritus | 0.522206 |
|
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| 1843 |
National Cancer Institute |
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Tratamiento del cáncer de vesícula biliar (PDQ®)–Versión para profesionales de salud |
Resumen de información revisada por expertos acerca del tratamiento del cáncer de vesícula biliar. |
| gemcitabina vs | 0.562266 |
| Compton CC | 0.670359 |
| Tsukada K | 0.846255 |
| Surg Oncol Clin | 0.680412 |
| situ carcinoma | 0.687891 |
| accessed october | 0.566163 |
| Trimodality therapy | 0.564056 |
| American Cancer Society | 0.950284 |
| 7th ed | 0.669585 |
| Estadio II–IV | 0.581785 |
| Chijiiwa K | 0.675106 |
| Surgical indications | 0.564187 |
| Instituto Nacional | 0.7169 |
| Primary carcinoma | 0.710358 |
| clasificación patológica t2 | 0.60477 |
| Uchida K | 0.58031 |
| enfermedad t2 | 0.580737 |
| Arch Surg | 0.626332 |
| Inapparent carcinoma | 0.891598 |
| determinados pacientes | 0.681197 |
| fármacos radiosensibilizadores | 0.863769 |
| biliary tract | 0.652373 |
| radical second operation | 0.814041 |
| Expandable metal stents | 0.585727 |
| estadio iv | 0.572834 |
|
| Cancer Facts | 0.649725 |
| surgical resection | 0.561157 |
| Shoup M | 0.562495 |
| Am Surg | 0.635005 |
| Cancer Staging Manual | 0.913061 |
| National Cancer Institute | 0.633613 |
| Surg Oncol | 0.770159 |
| from carcinoma | 0.694816 |
| PDQ Tratamiento | 0.671094 |
| New York | 0.64622 |
| second operation after | 0.820352 |
| tumor dissemination | 0.618784 |
| Physician Data Query | 0.581575 |
| Radiation therapy | 0.568753 |
| ganglios linfáticos n1 | 0.740227 |
| Yoshida K | 0.701223 |
| estadio focal iia | 0.6289 |
| Byrd DR | 0.659361 |
| after simple cholecystectomy | 0.807902 |
| Tis Carcinoma | 0.710719 |
| Am Coll Surg | 0.657212 |
| T)a aReproducción | 0.561453 |
| AJCC Cancer Staging | 0.929134 |
| Edge SB | 0.670645 |
|
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| 1884 |
National Cancer Institute |
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Tratamiento de las neoplasias de células plasmáticas (incluso mieloma múltiple) (PDQ®)–Versión para profesionales de salud |
Resumen de información revisada por expertos acerca del tratamiento de las neoplasias de células plasmáticas (incluso mieloma múltiple). |
| mieloma múltiple grupo | 0.317462 |
| multicentre randomized study | 0.314956 |
| Rajkumar SV | 0.360993 |
| Durie BG | 0.317277 |
| Dispenzieri A | 0.381536 |
| primary plasma cell | 0.32094 |
| Lacy MQ | 0.31455 |
| extramedullary plasmacytoma | 0.321972 |
| light chain | 0.421207 |
| Myeloma Study Group | 0.325182 |
| versus deferred treatment | 0.314362 |
| plasma cell | 0.333759 |
| monoclonal gammopathies | 0.324288 |
| Radiat Oncol Biol | 0.320101 |
| multiple myeloma | 0.968571 |
| systemic amyloidosis | 0.315374 |
| stem cell transplantation | 0.348134 |
| International Myeloma Working | 0.450729 |
| células plasmáticas tipo | 0.324338 |
| proteÃna m | 0.360491 |
| Rosiñol L | 0.316442 |
| patients with | 0.434191 |
| patients with primary | 0.318338 |
| plasma cell leukemia | 0.319942 |
| UK Myeloma Forum | 0.317407 |
|
| células madre | 0.338769 |
| Myeloma Working Group | 0.450073 |
| International Blood | 0.317358 |
| primary systemic amyloidosis | 0.314303 |
| peripheral blood stem | 0.321195 |
| células plasmáticas oligosecretoras | 0.325603 |
| Therneau TM | 0.332031 |
| monoclonal gammopathy | 0.501114 |
| Dimopoulos MA | 0.326344 |
| Kumar SK | 0.315489 |
| lesiones óseas | 0.347582 |
| light chain amyloidosis | 0.337292 |
| International Staging System | 0.324252 |
| monoclonal sérica tipo | 0.317411 |
| Kyle RA | 0.395277 |
| Clin Oncol | 0.474276 |
| myeloma with | 0.317498 |
| Oncol Biol Phys | 0.320425 |
| mieloma múltiple estadio | 0.31799 |
| Nordic Myeloma Study | 0.324636 |
| with newly diagnosed | 0.31487 |
| células plasmáticas neoplasia | 0.324857 |
| mieloma múltiple igg | 0.323238 |
| patients with newly | 0.318559 |
|
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| 1912 |
National Cancer Institute |
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es |
Tratamiento de la leucemia mieloide aguda y otras neoplasias mieloides malignas infantiles (PDQ®)–Versión para pacientes |
Resumen de información revisada por expertos acerca del tratamiento del cáncer de la leucemia mieloide aguda y otras neoplasias mieloides malignas infantiles. |
| sÃndromes mielodisplásicos.Quimioterapia | 0.302945 |
| linfocÃtica aguda | 0.307126 |
| siguientes procedimientos | 0.33161 |
| siguientes aspectos | 0.303162 |
| Neurofibromatosis tipo | 0.303799 |
| células madre formadoras | 0.308269 |
| siguientes especialistas | 0.302945 |
| hueso compacto | 0.308024 |
| neoplasias mieloides | 0.310246 |
| célula madre mieloide | 0.324347 |
| Bultos indoloros | 0.302618 |
| lÃquido cefalorraquÃdeo | 0.326401 |
| leucemia mielomonocÃtica | 0.41887 |
| Instituto Nacional | 0.305639 |
| célula madre linfoide | 0.318549 |
| siguientes problemas | 0.302781 |
| leucemia mielógena | 0.419565 |
| neoplasias mielodisplásicas | 0.302899 |
| LMA recién | 0.316713 |
| cáncer regrese).El | 0.307025 |
| madre mieloides | 0.328575 |
| células madre mieloides | 0.318746 |
| leucemia promielocÃtica aguda | 0.371662 |
| células madre | 0.977959 |
| leucemia mielógena aguda | 0.321693 |
|
| leucemia aguda | 0.310888 |
| leucemia linfoblástica aguda | 0.335277 |
| sÃndromes mielodisplásicos | 0.43219 |
| enlace drugs approved | 0.308769 |
| Acute Myeloid Leukemia | 0.309058 |
| infantil recidivante | 0.30755 |
| Sudores nocturnos | 0.302372 |
| efectos tardÃos | 0.309904 |
| médula ósea.Leucemia mielógena | 0.31318 |
| células cancerosas.El gemtuzumab | 0.309349 |
| punción espinal.Ampliar | 0.30255 |
| leucemia granulocÃtica aguda | 0.320187 |
| PDQ Tratamiento | 0.305949 |
| blastocitos mieloides | 0.303489 |
| tirosina cinasa | 0.339619 |
| sistema nervioso central | 0.381371 |
| leucemia mieloblástica aguda | 0.320188 |
| Physician Data Query | 0.305829 |
| enfermedades mieloides | 0.315553 |
| SMD)Algunos tratamientos | 0.302284 |
| revés.La prueba | 0.301997 |
| leucemia mieloide aguda | 0.981978 |
| célula madre | 0.354129 |
| siguientes sumarios | 0.305018 |
|
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| 2070 |
National Cancer Institute |
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Inhibidores de la angiogénesis |
Hoja informativa que describe el proceso de eliminación de suministro de sangre a los tumores. Incluye una lista de los cánceres en los que se está probando este enfoque. |
| vasos sanguÃneos resultantes | 0.32417 |
| NCIÂ de estudios | 0.304711 |
| llamadas metástasis | 0.305878 |
| posibles efectos | 0.304824 |
| Drug Administration | 0.306756 |
|
| células renales | 0.307581 |
| angiogénesis efectos | 0.326284 |
| Estados Unidos | 0.315596 |
| vasos sanguÃneos | 0.986577 |
|
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| 3605 |
National Cancer Institute |
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en |
Enhancing Drug Discovery and Development |
The discovery and development of new therapeutic agents for cancer is essential for continued progress against the disease. Historically, NCI has played a vital role in cancer drug discovery and development, and, today, that role continues. Frequently, NCI’s drug development efforts focus on unmet needs that are not being adequately addressed by the private sector. |
| human tumor cell | 0.493589 |
| Developmental Therapeutics Program | 0.373741 |
| cell lines | 0.756764 |
| corresponding cancer types | 0.401362 |
| primary cancer cells | 0.471158 |
| drug discovery | 0.918943 |
| cell line panel | 0.382826 |
| long-term cell cultures | 0.381121 |
| drug screening | 0.363881 |
| development activities | 0.393342 |
| human cancer models | 0.633791 |
| human tumor samples | 0.437784 |
| precision medicine | 0.432081 |
| congressionally mandated initiative | 0.360908 |
| human cancer cell | 0.54738 |
| drug resistance | 0.374751 |
| tyrosine kinase inhibitor | 0.365397 |
| drug development efforts | 0.451048 |
| potential anticancer agents | 0.404376 |
| traditional cell lines | 0.391913 |
| parental tumors | 0.388039 |
| routine cancer care | 0.38291 |
| Cancer Treatment | 0.353066 |
| cancer cells | 0.647891 |
| cancer cell lines | 0.473566 |
|
| new human cancer | 0.517038 |
| cancer cell biology | 0.425139 |
| NCI Experimental Therapeutics | 0.397544 |
| tumor sections | 0.354283 |
| cell line screen | 0.52167 |
| largest cancer pharmacology | 0.402164 |
| cell culture techniques | 0.37598 |
| NCI-60 cell line | 0.515114 |
| drug discovery program | 0.435482 |
| NIH Clinical Center | 0.354806 |
| cancer stem cells | 0.444759 |
| anticancer drug discovery | 0.568944 |
| biologic agent discovery | 0.381604 |
| new therapeutic agents | 0.383079 |
| Cancer Chemotherapy National | 0.425183 |
| NCI’s anticancer | 0.350161 |
| clinical development resources | 0.397358 |
| NCI’s drug | 0.370038 |
| original tumor | 0.350461 |
| normal cell counterparts | 0.370786 |
| cancer drug discovery | 0.678381 |
| Human cancer cells | 0.468312 |
| multiple cell types | 0.380725 |
| tumor microenvironment | 0.401449 |
|
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| 16680 |
National Cancer Institute |
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Cancer Moonshot℠ Implementation |
Implementation teams are considering multiple ways to fund new programs as well as expansions of ongoing efforts to advance the goals of the Cancer Moonshot. |
| Cancer Moonshot-related research | 0.688251 |
| ongoing efforts | 0.579887 |
| funding opportunity announcements | 0.69197 |
| authorization | 0.517804 |
| oversight | 0.515337 |
| Cancer Moonshot portfolio | 0.716496 |
| academia | 0.515431 |
| Cancer Moonshot goals | 0.684682 |
| Century Cures Act | 0.85793 |
| expansions | 0.51624 |
| implementation teams | 0.716347 |
| email Partnerships_CancerMoonshot | 0.582993 |
| list | 0.516345 |
| Scientific Advisors | 0.584259 |
| important role | 0.585193 |
| longer-term scientific initiatives | 0.700429 |
| research opportunities | 0.75591 |
| multiple ways | 0.591922 |
| private sector | 0.587499 |
| Cancer Moonshot | 0.987984 |
| Cancer Moonshot initiatives | 0.68956 |
| concept proposals | 0.656557 |
| automatic email | 0.583279 |
| receipt | 0.519207 |
|
| NCI intramural staff | 0.745934 |
| cancer research community | 0.682183 |
| NCI extramural program | 0.749793 |
| Program Leadership Committee | 0.655079 |
| potential partners | 0.586537 |
| available FOAs | 0.62206 |
| NCI’s Board | 0.674346 |
| NIH institutes | 0.582819 |
| existing funds | 0.59672 |
| new research opportunities | 0.683581 |
| 21st Century Cures | 0.861565 |
| scientific opportunities | 0.594628 |
| Blue Ribbon Panel | 0.846596 |
| BRP recommendation | 0.740701 |
| working groups | 0.588634 |
| new funding concepts | 0.653803 |
| BRP recommendations | 0.654047 |
| Public-private partnerships | 0.590589 |
| Cancer Moonshot implementation | 0.678145 |
| NCI advisory committees | 0.753041 |
| NCI’s Scientific | 0.67691 |
| report | 0.517155 |
| new programs | 0.586358 |
| funding mechanism | 0.587953 |
|
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| 16708 |
National Cancer Institute |
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en |
ALCHEMIST (The Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials): Questions and Answers |
ALCHEMIST represents three integrated, precision medicine trials that are designed to identify people with early-stage lung cancer who have tumors that harbor certain uncommon genetic changes and evaluate whether drug treatments targeted against those mol |
| certain genetic alterations | 0.511031 |
| ALK gene rearrangement | 0.86792 |
| specific genetic alterations | 0.510493 |
| lung cancer | 0.965003 |
| ALK genetic alterations | 0.561732 |
| component trials | 0.510228 |
| National Clinical Trials | 0.497396 |
| clinical trials | 0.62346 |
| early-stage lung cancer | 0.707269 |
| EGFR gene mutation | 0.628828 |
| best treatment approach | 0.483241 |
| lung cancers | 0.649896 |
| ALK Treatment component | 0.564764 |
| ECOG-ACRIN Cancer Research | 0.536673 |
| ALK rearrangement | 0.515701 |
| non-small cell lung | 0.519586 |
| Adjuvant Lung Cancer | 0.554841 |
| EGFR gene mutations | 0.510846 |
| uncommon genetic changes | 0.484048 |
| ALCHEMIST treatment trial | 0.613717 |
| new treatment approaches | 0.481108 |
| lung carcinoid tumors | 0.539366 |
| early-stage lung cancers | 0.57159 |
| appropriate ALCHEMIST treatment | 0.663904 |
|
| ALK gene | 0.888431 |
| precision medicine trials | 0.560161 |
| tumor tissue | 0.58358 |
| United States | 0.513049 |
| Dana-Farber Cancer Institute | 0.495276 |
| ALK alterations | 0.531283 |
| small cell lung | 0.519071 |
| National Cancer Institute | 0.484824 |
| ALCHEMIST study | 0.594796 |
| cancer risk characteristics | 0.487226 |
| EGFR Treatment component | 0.512344 |
| participants | 0.568322 |
| ALCHEMIST treatment trials | 0.868218 |
| genetic alterations | 0.637424 |
| complete surgical removal | 0.527484 |
| Cancer Research Group | 0.536403 |
| early-stage lung adenocarcinoma | 0.54246 |
| cell lung cancer | 0.575738 |
| Cancer Genomics | 0.482098 |
| FDA-approved Vysis ALK | 0.52631 |
| ALCHEMIST screening trial | 0.716569 |
| ALCHEMIST trials | 0.680442 |
| standard therapy | 0.505511 |
| Clinical Trials Agreement | 0.491455 |
|
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